Evidence map›Paper›PMID 24697281›Full record

ArticleAging & mental health2014

Association between schizophrenia symptoms and neurocognition on mobility in older adults with schizophrenia.

H Leutwyler, E Hubbard, D Jeste, B Miller, S Vinogradov

Abstract read
In one paragraph

Article in Aging & mental health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H Leutwylera Department of Physiological Nursing , University of California , San Francisco , CA , USA.
E Hubbard
D Jeste
B Miller
S Vinogradov

Funding

Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
Accelerated Inflammaging in SchizophreniaR01MH094151 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EYLER, LISA T · 2012 to 2021
$7.4M
Symptom Management Faculty Scholars ProgramP30NR011934 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIASKOWSKI, CHRISTINE A. · 2009 to 2010
$1.5M
Factors Associated to Poor Mobility in Older Adults with SchizophreniaK23AG044438 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEUTWYLER, HEATHER CHRISTINE · 2014 to 2016
$473k
NCATS NIH HHS KL2 TR000143NCATS NIH HHS KL2TR000143NIA NIH HHS K23 AG044438NIMH NIH HHS R01 MH094151NINR NIH HHS P30 NR011934NINR NIH HHS P30-NR011934-0
6 · The paper itself

Abstract

objectivesOlder persons with schizophrenia develop problems associated with aging, such as poor mobility, at more rapid rates than people without serious mental illness. Decrements in mobility contribute to poor health outcomes. Impaired neurocognitive function and psychiatric symptoms are central aspects of schizophrenia. The purpose of this study was to determine the association between neurocognitive impairment and schizophrenia symptoms to mobility in older adults with schizophrenia.

methodsA cross-sectional study with 46 older adults with schizophrenia. Participants were assessed on neurocognitive function (MATRICS Consensus Cognitive Battery), psychiatric symptoms (Positive and Negative Syndrome Scale or PANSS), and mobility (Timed Get Up and Go or TGUG test). Pearson's bivariate correlations (two-tailed) and a simultaneous regression model were used.

resultsLower severity of negative symptoms and faster speed of processing tests were associated with faster TGUG time in bivariate correlations and multivariate regression analyses (p < .05).

conclusionOur data suggest that lower negative symptoms and faster speed of processing positively impact mobility in older patients with schizophrenia. Mobility interventions for this population need to target neurocognitive impairment and schizophrenia symptoms for optimal results.

Indexed as

AgedCognition DisordersCross-Sectional StudiesFemaleHumansLocomotionMaleMiddle AgedMobility LimitationPsychotic DisordersSchizophreniaSeverity of Illness Indexcognitive functioningfunctional statusschizophrenia and paranoid disorders

Identifiers

PMID24697281
PMCPMC4177266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.