Evidence map›Paper›PMID 24696710›Full record

ArticleInternational journal of clinical and experimental pathology2014

Silencing SATB1 influences cell invasion, migration, proliferation, and drug resistance in nasopharyngeal carcinoma.

Chun-Sheng Ye, Dong-Ni Zhou, Qing-Qing Yang, Yan-Fei Deng

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. iTextMine: integrated text-mining system for large-scale knowledge extraction from the literature.Database : the journal of biological databases and curation · 2018
    Article
  6. Oncolytic virus carrying shRNA targeting SATB1 inhibits prostate cancer growth and metastasis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  7. Article
  8. SATB1 and 2 in colorectal cancer.Carcinogenesis · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chun-Sheng YeDepartment of Otolaryngology-Head and Neck Surgery, Zhongshan Hospital, Xiamen University Xiamen, China.
Dong-Ni ZhouDepartment of Pathology, Zhongshan Hospital, Xiamen University Xiamen, China.
Qing-Qing YangDepartment of Otolaryngology-Head and Neck Surgery, Union School of Clinical Medicine, Fujian Medical University Fuzhou, China.
Yan-Fei DengDepartment of Otolaryngology-Head and Neck Surgery, Zhongshan Hospital, Xiamen University Xiamen, China ; Department of Otolaryngology-Head and Neck Surgery, Union School of Clinical Medicine, Fujian Medical University Fuzhou, China.
Fujian Medical University · CNZhongshan Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Special AT rich sequence binding protein 1 (SATB1) play an important role in many cancers, but the role of SATB1 in nasopharyngeal carcinoma (NPC) is still not full understand. Immunofluorescence staining showed that SATB1 was mainly localized in the nuclei in CNE-2 cell. After successful down-regulation of SABT1 in NPC cell line CNE-2 by shRNA, compared to parental CNE-2 and control shRNA group, the capacity of the proliferation, migration, invasion and drug resistance of CNE-2 cell was reduced, which indicated that SATB1 may be involved in NPC development and progression. SATB1 may be a promising therapeutic target for nasopharyngeal carcinoma.

Indexed as

Cell MovementBlotting, WesternCarcinomaCell Line, TumorDrug Resistance, NeoplasmFluorescent Antibody TechniqueGene SilencingHumansMatrix Attachment Region Binding ProteinsNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNeoplasm InvasivenessReverse Transcriptase Polymerase Chain ReactionTransfectionMatrix Attachment Region Binding ProteinsSATB1 protein, humandrug resistanceinvasionNasopharyngeal carcinomaproliferationSATB1

Identifiers

PMID24696710
PMCPMC3971293
OpenAlexW314490482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.