ReviewWorld journal of gastroenterology2014
Microscopic features of colorectal neoplasia in inflammatory bowel diseases.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- An epithelial mesenchymal transition associated gene signature stratifies risk of ulcerative colitis associated colorectal cancer.Discover oncology · 2026Article
- p53 protein degradation redefines the initiation mechanisms and drives transitional mutations in colorectal cancer.Nature communications · 2025Article
- Colitis-Associated Dysplasia in Inflammatory Bowel Disease: Features and Endoscopic Management.Cancers · 2025Review
- Architectural crypt distortions in ulcerative colitis: Time for reappraisal.Journal of gastroenterology and hepatology · 2024Review
- Advancements in Endoscopic Resection for Colitis-Associated Colorectal Neoplasia in Inflammatory Bowel Disease: Turning Visible into Resectable.Diagnostics (Basel, Switzerland) · 2023Review
- Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects.Molecular medicine reports · 2022Article
- Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer.Cell · 2021Article
- MicroRNA expression in inflammatory bowel disease-associated colorectal cancer.World journal of gastrointestinal oncology · 2021Review
- MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade.Scientific reports · 2021Article
- Diagnostic interobserver variability in Crohn's disease- and ulcerative colitis-associated dysplasia: a multicenter digital survey from the IG-IBD Pathologists Group.Techniques in coloproctology · 2021Article
- Genomic and molecular alterations in human inflammatory bowel disease-associated colorectal cancer.United European gastroenterology journal · 2020Review
- Non-conventional mucosal lesions (serrated epithelial change, villous hypermucinous change) are frequent in patients with inflammatory bowel disease-results of molecular and immunohistochemical single institutional study.Virchows Archiv : an international journal of pathology · 2020Article
- Genomic characterization of colitis-associated colorectal cancer.World journal of surgical oncology · 2018Review
- Colorectal Cancer Blood-Based Biomarkers.Gastroenterology research and practice · 2017Review
- Biomarkers for colitis-associated colorectal cancer.World journal of gastroenterology · 2016Review
- The role of adipose stem cells in inflammatory bowel disease: From biology to novel therapeutic strategies.Cancer biology & therapy · 2016Review
- Anal Canal Adenocarcinoma in a Patient with Longstanding Crohn's Disease Arising From Rectal Mucosa that Migrated From a Previously Treated Rectovaginal Fistula.The American journal of case reports · 2016Article
- Establishment and characterization of HROC69 - a Crohn´s related colonic carcinoma cell line and its matched patient-derived xenograft.Scientific reports · 2016Article
- Colitis-associated colon cancer: Is it in your genes?World journal of gastroenterology · 2015Review
- Molecular Alterations of Colorectal Cancer with Inflammatory Bowel Disease.Digestive diseases and sciences · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The risk of developing dysplasia leading to colorectal cancer (CRC) is increased in both ulcerative colitis and Crohn's disease. The prognosis of CRC may be poorer in patients with inflammatory bowel disease (IBD) than in those without IBD. Most CRCs, in general, develop from a dysplastic precursor lesion. The interpretation by the pathologist of the biopsy will guide decision making in clinical practice: colonoscopic surveillance or surgical management. This review summarizes features of dysplasia (or intraepithelial neoplasia) with macroscopic and microscopic characteristics. From an endoscopic (gross) point of view, dysplasia may be classified as flat or elevated (raised); from a histological point of view, dysplasia is separated into 3 distinct categories: negative for dysplasia, indefinite for dysplasia, and positive for dysplasia with low- or high-grade dysplasia. The morphologic criteria for dysplasia are based on a combination of cytologic (nuclear and cytoplasmic) and architectural aberrations of the crypt epithelium. Immunohistochemical and molecular markers for dysplasia are reviewed and may help with dysplasia diagnosis, although diagnosis is essentially based on morphological criteria. The clinical, epidemiologic, and pathologic characteristics of IBD-related cancers are, in many aspects, different from those that occur sporadically in the general population. Herein, we summarize macroscopic and microscopic features of IBD-related colorectal carcinoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.