ArticleOccupational and environmental medicine2014
Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study.
Article in Occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Distance to a Drying Saline Lake and Lung Function Development in a Rural Border Cohort of Children.JAMA network open · 2026Article
- Particulate matter levels and children's lung function in a rural cohort near a drying saline lake.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Ligand spin immobilization in metal-organic frameworks enables high-performance chemispintronic detection of radical gas molecules.Science advances · 2025Article
- Long-term PMPediatric research · 2025Article
- Airway inflammation, asthma, and soot.Pediatric research · 2025Article
- Short-term, lagged association of airway inflammation, lung function, and asthma symptom score with PMEnvironmental epidemiology (Philadelphia, Pa.) · 2024Article
- Cohort profile: The Assessing Imperial Valley Respiratory Health and the Environment (AIRE) study.Paediatric and perinatal epidemiology · 2024Article
- The Influence of Short-Term Weather Parameters and Air Pollution on Adolescent Airway Inflammation.International journal of environmental research and public health · 2023Article
- Article
- Underground salt and potash workers exposed to nitrogen oxides and diesel exhaust: assessment of specific effect biomarkers.International archives of occupational and environmental health · 2022Article
- Long-term exposures to air pollutants affectThe European respiratory journal · 2021Article
- Personal Exposure to Black Carbon at School and Levels of Fractional Exhaled Nitric Oxide in New York City.Environmental health perspectives · 2021Article
- Interstitial Lung Diseases and Air Pollution: Narrative Review of Literature.Pulmonary therapy · 2021Review
- Assessing the Respiratory Effects of Air Pollution from Biomass Cookstoves on Pregnant Women in Rural India.International journal of environmental research and public health · 2020Article
- Fractional exhaled nitric oxide and respiratory complaints in Hajj pilgrims wearing a cotton towel or plain cotton ihram.The Journal of international medical research · 2020Article
- Viruses and non-allergen environmental triggers in asthma.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2019Review
- Associations of Timing and Mode of Commuting with In-Transit Black Carbon Exposure and Airway Inflammation: A Pilot Study.Annals of the American Thoracic Society · 2019Article
- Source-specific pollution exposure and associations with pulmonary response in the Atlanta Commuters Exposure Studies.Journal of exposure science & environmental epidemiology · 2018Article
- Genetic and epigenetic susceptibility of airway inflammation to PMEnvironmental health : a global access science source · 2017Article
- Comparison of the Fractional Exhaled Nitric Oxide Levels in Adolescents at Three Schools Located Three Different Distances from a Large Steel Mill.Canadian respiratory journal · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesTo assess the effects of long-term variations in ambient air pollutants on longitudinal changes in exhaled nitric oxide (FeNO), a potentially useful biomarker of eosinophilic airway inflammation, based on data from the southern California Children's Health Study.
methodsBased on a cohort of 1211 schoolchildren from eight Southern California communities with FeNO measurements in 2006-2007 and 2007-2008, regression models adjusted for short-term effects of air pollution were fitted to assess the association between changes in annual long-term exposures and changes in FeNO.
resultsIncreases in annual average concentrations of 24-h average NO2 and PM2.5 (scaled to the IQR of 1.8 ppb and 2.4 μg/m(3), respectively) were associated with a 2.29 ppb (CI 0.36 to 4.21; p=0.02) and a 4.94 ppb (CI 1.44 to 8.47; p=0.005) increase in FeNO, respectively, after adjustments for short-term effects of the respective pollutants. In contrast, changes in annual averages of PM10 and O3 were not significantly associated with changes in FeNO. These findings did not differ significantly by asthma status.
conclusionsChanges in annual average exposure to current levels of ambient air pollutants are significantly associated with changes in FeNO levels in children, independent of short-term exposures and asthma status. Use of this biomarker in population-based epidemiological research has great potential for assessing the impact of changing real world mixtures of ambient air pollutants on children's respiratory health.
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