Evidence map›Paper›PMID 24696494›Full record

ArticleJournal of virology2014

Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod-shaped virus 2.

Andrew F Gardner, Stephen D Bell, Malcolm F White, David Prangishvili, Mart Krupovic

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The enigmatic archaeal virosphere.Nature reviews. Microbiology · 2017
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Andrew F GardnerNew England Biolabs, Ipswich, Massachusetts, USA.
Stephen D BellMolecular and Cellular Biochemistry Department and Biology Department, Indiana University, Bloomington, Indiana, USA.
Malcolm F WhiteBiomedical Sciences Research Complex, University of St Andrews, Fife, United Kingdom.
David PrangishviliInstitut Pasteur, Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Département de Microbiologie, Paris, France krupovic@pasteur.fr david.prangishvili@pasteur.fr.
Mart KrupovicInstitut Pasteur, Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Département de Microbiologie, Paris, France krupovic@pasteur.fr david.prangishvili@pasteur.fr.
Biology of Extremophiles Laboratory · FRIndiana University Bloomington · USInstitut Pasteur · FRNew England Biolabs (United States) · USUniversity of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses infecting hyperthermophilic archaea typically do not encode DNA polymerases, raising questions regarding their genome replication. Here, using a yeast two-hybrid approach, we have assessed interactions between proteins of Sulfolobus islandicus rod-shaped virus 2 (SIRV2) and the host-encoded proliferating cell nuclear antigen (PCNA), a key DNA replication protein in archaea. Five SIRV2 proteins were found to interact with PCNA, providing insights into the recruitment of host replisome for viral DNA replication.

Indexed as

Amino Acid SequenceArchaeal ProteinsDNA, ArchaealModels, MolecularMolecular Sequence DataProliferating Cell Nuclear AntigenProtein BindingRudiviridaeSulfolobusViral ProteinsVirus ReplicationArchaeal ProteinsDNA, ArchaealProliferating Cell Nuclear AntigenViral Proteins

Identifiers

PMID24696494
PMCPMC4054388
OpenAlexW1981983390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.