ArticleThe international journal of cardiovascular imaging2014
Direct comparison of stress- and rest-dual-energy computed tomography for detection of myocardial perfusion defect.
Article in The international journal of cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020Review
- Narrative review of cardiac computed tomography perfusion: insights into static rest perfusion.Cardiovascular diagnosis and therapy · 2020Review
- Role of DECT in coronary artery disease: a comparative study with ICA and SPECT.Diagnostic and interventional radiology (Ankara, Turkey) · 2020Article
- Dual-energy CT and coronary imaging.Cardiovascular diagnosis and therapy · 2020Review
- Computed tomography for myocardial characterization in ischemic heart disease: a state-of-the-art review.European radiology experimental · 2020Review
- [Evaluation of Myocardial Ischemia Using Coronary Computed Tomography Angiography in Patients with Stable Angina].Taehan Yongsang Uihakhoe chi · 2020Review
- Article
- Myocardial Assessment with Cardiac CT: Ischemic Heart Disease and Beyond.Current cardiovascular imaging reports · 2018Review
- CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging.BioMed research international · 2018Review
- Myocardial ischemia testing with computed tomography: emerging strategies.Cardiovascular diagnosis and therapy · 2017Review
- Myocardial computed tomography perfusion.Cardiovascular diagnosis and therapy · 2017Review
- Computed tomography of cardiomyopathies.Cardiovascular diagnosis and therapy · 2017Review
- CT myocardial perfusion imaging: current status and future perspectives.The international journal of cardiovascular imaging · 2017Review
- Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography.Cardiovascular diagnosis and therapy · 2017Review
- Update on Computed Tomography Myocardial Perfusion Imaging.Current cardiovascular imaging reports · 2016Article
- CT-based myocardial ischemia evaluation: quantitative angiography, transluminal attenuation gradient, myocardial perfusion, and CT-derived fractional flow reserve.The international journal of cardiovascular imaging · 2016Review
- Dual-energy computed tomography for detection of coronary artery disease.Expert review of cardiovascular therapy · 2015Review
- New Applications of Cardiac Computed Tomography: Dual-Energy, Spectral, and Molecular CT Imaging.JACC. Cardiovascular imaging · 2015Review
- Cardiovascular imaging 2014 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2015Review
- Noninvasive physiologic assessment of coronary stenoses using cardiac CT.BioMed research international · 2015Review
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
We assessed the diagnostic performance of stress- and rest-dual-energy computed tomography (DECT) and their incremental value when used with coronary CT angiography (CCTA) compared with combined invasive coronary angiography (ICA)/cardiovascular magnetic resonance (CMR) for detecting hemodynamically significant stenosis causing a myocardial perfusion defect. Forty patients (30 men; mean age, 63.4 ± 8.8 years) with known or suspected coronary artery disease detected by CCTA underwent stress- and rest-DECT, CMR, and ICA. DECT iodine maps were compared with CMR on a per-segment and per-vessel basis. Diagnostic value of CCTA was assessed on a per-vessel basis before and after stress- and rest-DECT and compared to that of ICA/CMR. Compared to CMR, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of rest-DECT for detecting segment (vessel)-based perfusion defects were 29% (46%), 88% (79%), 56% (61%), and 70% (67%), respectively. Corresponding values using stress-DECT were 73% (94%), 83% (74%), 70% (72%), and 85% (95%), respectively. There was fair (κ = 0.39) agreement between rest- and stress-DECT iodine maps in identifying segments with perfusion defects. Compared with the ICA/CMR for identifying hemodynamically significant stenoses, per-vessel territory sensitivity, specificity, PPV, and NPV of CCTA were 91, 56, 55, and 91%, respectively; those using CCTA/rest-DECT were 42, 83, 59, and 70%, respectively; and those using CCTA/stress-DECT were 87, 79, 71, and 91%, respectively. The area under the receiver operating characteristic curve decreased from 0.74 to 0.62 (P = 0.06) using CCTA/rest-DECT but increased to 0.83 (P = 0.02) using CCTA/stress-DECT. Stress-DECT has incremental value when used with CCTA for detecting hemodynamically significant stenoses.
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