ArticleJournal of biomedical optics2014
Numerical simulation of x-ray luminescence optical tomography for small-animal imaging.
Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Superfast Scan of Focused X-Ray Luminescence Computed Tomography Imaging.IEEE access : practical innovations, open solutions · 2023Article
- Contrast agents for x-ray luminescence computed tomography.Applied optics · 2021Article
- Focused x-ray luminescence imaging system for small animals based on a rotary gantry.Journal of biomedical optics · 2021Article
- Radiation dose estimation for pencil beam X-ray luminescence computed tomography imaging.Journal of X-ray science and technology · 2021Article
- Review of in vivo optical molecular imaging and sensing from x-ray excitation.Journal of biomedical optics · 2021Review
- Restarted primal-dual Newton conjugate gradient method for enhanced spatial resolution of reconstructed cone-beam x-ray luminescence computed tomography images.Physics in medicine and biology · 2020Article
- High-resolution x-ray luminescence computed tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- X-ray luminescence imaging for small animals.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Limited view cone-beam x-ray luminescence tomography based on depth compensation and group sparsity prior.Journal of biomedical optics · 2020Article
- Method for improving the spatial resolution of narrow x-ray beam-based x-ray luminescence computed tomography imaging.Journal of biomedical optics · 2019Article
- Focused x-ray luminescence computed tomography: experimental studies.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Background luminescence in x-ray luminescence computed tomography (XLCT) imaging.Applied optics · 2019Article
- Time domain X-ray luminescence computed tomography: numerical simulations.Biomedical optics express · 2019Article
- Sensitivity evaluation and selective plane imaging geometry for x-ray-induced luminescence imaging.Medical physics · 2017Article
- Resolving adjacent nanophosphors of different concentrations by excitation-based cone-beam X-ray luminescence tomography.Biomedical optics express · 2017Article
- Sensitivity study of x-ray luminescence computed tomography.Applied optics · 2017Article
- Collimated superfine x-ray beam based x-ray luminescence computed tomography.Journal of X-ray science and technology · 2017Article
- Cone Beam X-ray Luminescence Computed Tomography Based on Bayesian Method.IEEE transactions on medical imaging · 2017Article
- Multiple pinhole collimator based X-ray luminescence computed tomography.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
X-ray luminescence optical tomography (XLOT) is an emerging hybrid imaging modality in which x-ray excitable particles (phosphor particles) emit optical photons when stimulated with a collimated x-ray beam. XLOT can potentially combine the high sensitivity of optical imaging with the high spatial resolution of x-ray imaging. For reconstruction of XLOT data, we compared two reconstruction algorithms, conventional filtered backprojection (FBP) and a new algorithm, x-ray luminescence optical tomography with excitation priors (XLOT-EP), in which photon propagation is modeled with the diffusion equation and the x-ray beam positions are used as reconstruction priors. Numerical simulations based on dose calculations were used to validate the proposed XLOT imaging system and the reconstruction algorithms. Simulation results showed nanoparticle concentrations reconstructed with XLOT-EP are much less dependent on scan depth than those obtained with FBP. Measurements at just two orthogonal projections are sufficient for XLOT-EP to reconstruct an XLOT image for simple source distributions. The heterogeneity of x-ray energy deposition is included in the XLOT-EP reconstruction and improves the reconstruction accuracy, suggesting that there is a need to calculate the x-ray energy distribution for experimental XLOT imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.