ArticlePloS one2014
Hospital admissions for hypertensive crisis in the emergency departments: a large multicenter Italian study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 4 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Clinical Outcomes in Hypertensive Emergency: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2023Pooled it
- A Systematic Review and Meta-analysis of the Clinical and Epidemiological Characteristics of Patients with Hypertensive Emergencies: Implication for Risk Stratification.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Pooled it
- ESC Council on hypertension position document on the management of hypertensive emergencies.European heart journal. Cardiovascular pharmacotherapy · 2019Guideline
- 7th Brazilian Guideline of Arterial Hypertension: Chapter 14 - Hypertensive CrisisArquivos brasileiros de cardiologia · 2016Guideline
- Sex-specific differences in clinical characteristics and organ damage in Hypertensive Urgencies.Internal and emergency medicine · 2026Observational
- Article
- Drug-associated hypertensive crisis: a disproportionality analysis of the FAERS database.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Hypertensive crisis in the critically ill.Annals of intensive care · 2026Review
- [Core curriculum of intensive care and emergency medicine in internal medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Review
- Hypertensive urgencies and emergencies in the cardiology emergency department: epidemiology, patient profile, and management.Journal of human hypertension · 2025Observational
- Comparison of Serum proBNP and Apelin Levels in Hypertensive Crisis Versus Controlled Hypertension: Impact of Opium Addiction Status.Addiction & health · 2025Article
- [Clinical acute and emergency medicine curriculum-focus on internal medicine : Recommendations for advanced training in internal medicine in the emergency department].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Review
- Slow on the Draw-ED Management of Elevated BP in Older Adults.Current hypertension reports · 2024Review
- Prevalence, trends, and factors associated with hypertensive crisis among Peruvian adults.Cadernos de saude publica · 2024Article
- The effect of combining therapeutic drug monitoring of antihypertensive drugs with personalised feedback on adherence and resistant hypertension: the (RHYME-RCT) trial protocol of a multi-centre randomised controlled trial.BMC cardiovascular disorders · 2023Article
- Prevalence of neurological complaints among emergency department patients with severe hypertension.The American journal of emergency medicine · 2023Article
- Article
- Prevalence of Myocardial Injury and Myocardial Infarction in Patients with a Hypertensive Emergency: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- Differences in Diagnosis and Management of Hypertensive Urgencies and Emergencies According to Italian Doctors from Different Departments Who Deal With Acute Increase in Blood Pressure-Data from Gear (Gestione Dell'emergenza e Urgenza in ARea Critica) Study.Journal of clinical medicine · 2022Article
- [The hypertensive emergency situation : Recommendations for initial drug therapy management].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2022Review
Corrections and comments
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Authors and funding
24 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological data on the impact of hypertensive crises (emergencies and urgencies) on referral to the Emergency Departments (EDs) are lacking, in spite of the evidence that they may be life-threatening conditions. We performed a multicenter study to identify all patients aged 18 years and over who were admitted to 10 Italian EDs during 2009 for hypertensive crises (systolic blood pressure ≥220 mmHg and/or diastolic blood pressure ≥120 mmHg). We classified patients as affected by either hypertensive emergencies or hypertensive urgencies depending on the presence or the absence of progressive target organ damage, respectively. Logistic regression analysis was then performed to assess variables independently associated with hypertensive emergencies with respect to hypertensive urgencies. Of 333,407 patients admitted to the EDs over the one-year period, 1,546 had hypertensive crises (4.6/1,000, 95% CI 4.4-4.9), and 23% of them had unknown hypertension. Hypertensive emergencies (n = 391, 25.3% of hypertensive crises) were acute pulmonary edema (30.9%), stroke (22.0%,), myocardial infarction (17.9%), acute aortic dissection (7.9%), acute renal failure (5.9%) and hypertensive encephalopathy (4.9%). Men had higher frequency than women of unknown hypertension (27.9% vs 18.5%, p<0.001). Even among known hypertensive patients, a larger proportion of men than women reported not taking anti-hypertensive drug (12.6% among men and 9.4% among women (p<0.001). Compared to women of similar age, men had higher likelihood of having hypertensive emergencies than urgencies (OR = 1.34, 95% CI 1.06-1.70), independently of presenting symptoms, creatinine, smoking habit and known hypertension. This study shows that hypertensive crises involved almost 5 out of 1,000 patients-year admitted to EDs. Sex differences in frequencies of unknown hypertension, compliance to treatment and risk of hypertensive emergencies might have implications for public health programs.
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