Trial reportPloS one2014
Prognosis of 18 H7N9 avian influenza patients in Shanghai.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Analysis of clinical characteristics and risk factors for death due to severe influenza in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- A dynamic model for individualized prognosis prediction in patients with avian influenza A H7N9.Annals of translational medicine · 2022Article
- Designing a multi-epitope vaccine to provoke the robust immune response against influenza A H7N9.Scientific reports · 2021Article
- Update Advances on C-Reactive Protein in COVID-19 and Other Viral Infections.Frontiers in immunology · 2021Review
- Thrombo-inflammatory features predicting mortality in patients with COVID-19: The FAD-85 score.The Journal of international medical research · 2020Observational
- Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia.Science advances · 2020Article
- Long-term clinical prognosis of human infections with avian influenza A(H7N9) viruses in China after hospitalization.EClinicalMedicine · 2020Article
- Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China.BMC infectious diseases · 2016Article
- Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.Scientific reports · 2016Article
- Long-term Follow-up of 5 Survivors after the First Outbreak of Human Infections with Avian Influenza A(H7N9) Virus in Shanghai, China.Chinese medical journal · 2016Article
- Aberrant coagulation causes a hyper-inflammatory response in severe influenza pneumonia.Cellular & molecular immunology · 2016Review
- Multiple gene mutations identified in patients infected with influenza A (H7N9) virus.Scientific reports · 2016Article
- Genotyping and detection of common avian and human origin-influenza viruses using a portable chemiluminescence imaging microarray.SpringerPlus · 2016Article
- Prognosis and survival of 128 patients with severe avian influenza A(H7N9) infection in Zhejiang province, China.Epidemiology and infection · 2015Article
- Double encephalitis with herpes simplex virus type II and cytomegalovirus in an elder Chinese: a case report.Neuropsychiatric disease and treatment · 2015Article
- Pandemic potential of avian influenza A (H7N9) viruses.Trends in microbiology · 2014Review
Corrections and comments
- Erratum issued
Authors and funding
16 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo provide prognosis of an 18 patient cohort who were confirmed to have H7N9 lung infection in Shanghai.
methodsPatients' history, clinical manifestation, laboratory test, treatment strategy and mortality were followed and recorded for data analysis.
resultsA total of 18 patients had been admitted into Shanghai Public Health Clinical Center from April 8th to July 29, 2013. 22.2% of the patients were found to have live poultry contact history and 80% were aged male patients with multiple co-morbidities including diabetes, hypertension and/or chronic obstructive pulmonary disease (COPD). This group of patients was admitted to the clinical center around 10 days after disease onset. According to laboratory examinations, increased C reactive protein (CRP), Procalcitonin (PCT), Plasma thromboplastin antecedent (PTA) and virus positive time (days) were indicative of patients' mortality. After multivariate analysis, only CRP level showed significant prediction of mortality (P = 0.013) while results of prothrombin time (PT) analysis almost reached statistical significance (P = 0.056).
conclusionsH7N9 infection induced pneumonia of different severity ranging from mild to severe pneumonia or acute lung injury/acute respiratory distress syndrome to multiple organ failure. Certain laboratory parameters such as plasma CRP, PCT, PTA and virus positive days predicted mortality of H7N9 infection and plasma CRP is an independent predictor of mortality in these patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.