Evidence map›Paper›PMID 24695171›Full record

ArticleJournal of the Optical Society of America. A, Optics, image science, and vision2014

Cone-isolating ON-OFF electroretinogram for studying chromatic pathways in the retina.

James A Kuchenbecker, Scott H Greenwald, Maureen Neitz, Jay Neitz

Abstract read
In one paragraph

Article in Journal of the Optical Society of America. A, Optics, image science, and vision, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Intermixing theGenes · 2021
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James A Kuchenbecker
Scott H Greenwald
Maureen Neitz
Jay Neitz

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Vision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI Jay Neitz · 1985 to 2026
$23.5M
VISUAL SCIENCES TRAINING PROGRAMT32EY007031 · NEI · UNIVERSITY OF WASHINGTON · PI Wyeth Daniel Bair, Anitha Pasupathy · 1985 to 2026
$6.1M
GENES AND VISUAL PIGMENTS OF RED/GREEN COLOR VISIONR01EY009303 · NEI · UNIVERSITY OF WASHINGTON · PI NEITZ, MAUREEN E · 1991 to 2013
$5.2M
GENETIC ANALYSIS OF DROSOPHILA EPH RECEPTOR SIGNALINGF32EY007030 · NEI · HARVARD UNIVERSITY · PI DEARBORN, RICHARD E · 1999 to 2002
$86k
NEI NIH HHS F32 EY007030NEI NIH HHS P30 EY001730NEI NIH HHS P30EY01730NEI NIH HHS R01 EY009303NEI NIH HHS R01EY09303NEI NIH HHS T32EY007030NEI NIH HHS T32 EY007031NIH HHS P51 OD010425
6 · The paper itself

Abstract

The electroretinogram (ERG) provides information about outer retina function in both clinical and research applications. ERG components elicited by light increments and decrements can be separated using a long-flash paradigm in which periods of light ON and OFF are alternated. Here, the ON-OFF ERG is combined with a silent substitution technique to elicit responses from individual cone photoreceptor classes by modulating the intensities of three color lights between the two periods. The results focus on the short wavelength (S) cone pathways since they are vulnerable to disease and because there are many unanswered questions about S-cone ON and OFF circuitry.

Indexed as

Signal TransductionAnimalsColor PerceptionElectroretinographyHumansPapioRetinal Cone Photoreceptor Cells

Identifiers

PMID24695171
PMCPMC4143118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.