Evidence map›Paper›PMID 24695064›Full record

Trial reportRetina (Philadelphia, Pa.)2014

Fluorescein angiography versus optical coherence tomography-guided planning for macular laser photocoagulation in diabetic macular edema.

Igor Kozak, Sharif Y El-Emam, Lingyun Cheng, Dirk-Uwe Bartsch, Jay Chhablani, William R Freeman, J Fernando Arevalo

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Retina (Philadelphia, Pa.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Multi-label classification of retinal lesions in diabetic retinopathy for automatic analysis of fundus fluorescein angiography based on deep learning.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Treatment decisions in diabetic macular edema based on optical coherence tomography retinal thickness map: LET classification.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Igor Kozak*Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; †Jacobs Retina Center, University of California San Diego, La Jolla, California; ‡LV Prasad Eye Institute, Hyderabad, India; and §Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland.
Sharif Y El-Emam
Lingyun Cheng
Dirk-Uwe Bartsch
Jay Chhablani
William R Freeman
J Fernando Arevalo
University of California, San Diego · USKing Khaled Eye Specialist Hospital · SAJacobs (United States) · USL V Prasad Eye Institute · IN

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2012 to 2026
$10.3M
Mechanistic-Based Non-Invasive Assessment of Retinal Damage in HAART EraR01EY016323 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARTSCH, DIRK-UWE G · 2006 to 2020
$5.0M
NCI NIH HHS P30 CA006973NEI NIH HHS P30 EY022589NEI NIH HHS R01 EY016323
6 · The paper itself

Abstract

purposeTo compare laser photocoagulation plans for diabetic macular edema (DME) using fluorescein angiography (FA) versus optical coherence tomography (OCT) thickness map superimposed on the retina.

methodsFourteen eyes with DME undergoing navigated laser photocoagulation with navigated photocoagulator had FA taken using the same instrument. Optical coherence tomography central retinal thickness map was imported to the photocoagulator and with same magnification aligned onto the retina. Three retina specialists placed laser spot marks separately on FA and OCT image in a masked fashion. The spots placed by each physician were compared between FA and OCT and among physicians. The area of dye leakage on FA and increased central retinal thickness on OCT of the same eye were also compared.

resultsThe average number of spots using FA and OCT template was 36.64 and 40.61, respectively (P = 0.0201). The average area of dye leakage was 7.45 mm, whereas the average area of increased central retinal thickness on OCT of the same eye was 10.92 mm (P = 0.013).

conclusionThere is variability in the treatment planning for macular photocoagulation with a tendency to place more spots when guided by OCT than by FA. Integration of OCT map aligned to the retina may have an impact on treatment plan once such information is available.

Indexed as

Fluorescein AngiographyLaser CoagulationTomography, Optical CoherenceDiabetic RetinopathyDouble-Blind MethodFemaleHumansMacula LuteaMacular EdemaMaleMiddle AgedProspective StudiesSurgery, Computer-AssistedVisual Acuity

Identifiers

PMID24695064
PMCPMC4695978
OpenAlexW2008452247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.