Evidence map›Paper›PMID 24694994›Full record

Trial reportPloS one2014

Timing and intensity of light correlate with body weight in adults.

Kathryn J Reid, Giovanni Santostasi, Kelly G Baron, John Wilson, Joseph Kang, Phyllis C Zee

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00246454 completednot on this map

Circadian Rhythms and Sleep in Familial Delayed Sleep Phase Syndrome (DSPS) and Advanced Sleep Phase Syndrome (ASPS)

TypeobservationalSponsorNorthwestern UniversityRan2003 to 2024Enrolled156ConditionsCircadian Rhythm Sleep Disorder
NCT02835261 nacompletednot on this mapstarted 2016, after this paper: background citation

Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women

TypeinterventionalSponsorColumbia UniversityRan2016 to 2021Enrolled54ConditionsSleep, Cardiovascular Disease, ObesityArmsSleep Restriction
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathryn J ReidDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.
Giovanni SantostasiDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.
Kelly G BaronDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.
John WilsonDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.
Joseph KangDepartment of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.
Phyllis C ZeeDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States of America.

Funding

SLOW WAVE SLEEP AND TYPE 2 DIABETES RISK IN AGINGP01AG011412 · NIA · UNIVERSITY OF CHICAGO · PI ZEE, PHYLLIS C. · 1994 to 2021
$31.5M
Career Development in Women's Health (CDWH)K12HD055884 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DUNAIF, ANDREA E · 2007 to 2016
$4.2M
Circadian rhythms and sleep in familial DSPS and ASPSR01HL069988 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZEE, PHYLLIS C · 2003 to 2007
$1.8M
Circadian Timing, Sleep, and AdiposityK23HL109110 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BARON, KELLY GLAZER · 2011 to 2014
$529k
NHLBI NIH HHS 1K23HL109110NHLBI NIH HHS K23 HL109110NHLBI NIH HHS R01 HL069988NHLBI NIH HHS R01HL069988NIA NIH HHS P01 AG011412NIA NIH HHS P01 AG11412NICHD NIH HHS 5K12 HD055884NICHD NIH HHS K12 HD055884
6 · The paper itself

Abstract

Light exposure can influence sleep and circadian timing, both of which have been shown to influence weight regulation. The goal of this study was to evaluate the relationship between ambient light, sleep and body mass index. Participants included 54 individuals (26 males, mean age 30.6, SD = 11.7 years). Light levels, sleep midpoint and duration were measured with wrist actigraphy (Actiwatch-L) for 7 days. BMI was derived from self-reported height and weight. Caloric intake was determined from 7 days of food logs. For each participant, light and activity data were output in 2 minute epochs, smoothed using a 5 point (10 minute) moving average and then aggregated over 24 hours. The mean light timing above 500 lux (MLiT500) was defined as the average clock time of all aggregated data points above 500 lux. MLiT500 was positively correlated with BMI (r = 0.51, p<0.001), and midpoint of sleep (r = 0.47, p<0.01). In a multivariable linear regression model including MLiT500 and midpoint of sleep, MLiT500 was a significant predictor of BMI (B = 1.26 SE = 0.34, β = 0.53 p = 0.001, r2Δ = 0.22). Adjusting for covariates, MLiT500 remained an independent predictor of BMI (B = 1.28 SE = 0.36, β = 0.54, p = 0.002, r2Δ = 0.20). The full model accounted for 34.7% of the variance in BMI (p = 0.01). Exposure to moderate levels of light at biologically appropriate times can influence weight, independent of sleep timing and duration.

Indexed as

Body Mass IndexLightingModels, BiologicalAdultCircadian RhythmEnergy IntakeFemaleHumansLightMaleSleepTime Factors

Identifiers

PMID24694994
PMCPMC3973603

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.