Trial reportMedicine and science in sports and exercise2014
Nonexercise energy expenditure and physical activity in the Midwest Exercise Trial 2.
Trial report in Medicine and science in sports and exercise, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Exercise Training on Non-Exercise Physical Activity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- Aerobic exercise elevates perceived appetite but does not modify energy intake over a 3-day postexercise period: A pilot study.Physiological reports · 2024Trial
- Compensatory mechanisms from different exercise intensities in type 2 diabetes: a secondary analysis of a 1-year randomized controlled trial.Acta diabetologica · 2023Trial
- Sedentary behavior and compensatory mechanisms in response to different doses of exercise-a randomized controlled trial in overweight and obese adults.European journal of clinical nutrition · 2017Trial
- Dose-response effects of aerobic exercise on energy compensation in postmenopausal women: combined results from two randomized controlled trials.International journal of obesity (2005) · 2017Trial
- Energy expenditure responses to exercise training in older women.Physiological reports · 2017Trial
- Energy and Macronutrient Intake in the Midwest Exercise Trial 2 (MET-2).Medicine and science in sports and exercise · 2015Trial
- Validity of energy intake estimated by digital photography plus recall in overweight and obese young adults.Journal of the Academy of Nutrition and Dietetics · 2015Trial
- Energy intake, nonexercise physical activity, and weight loss in responders and nonresponders: The Midwest Exercise Trial 2.Obesity (Silver Spring, Md.) · 2015Trial
- Energy constraint on human health.Trends in endocrinology and metabolism: TEM · 2026Review
- Frequency-dependent adaptations in energy expenditure, strength, mood, and inflammation following 16 to 32 weeks of combined aerobic and resistance training in older women.European journal of applied physiology · 2026Article
- Multilevel metabolic adaptation to exercise training.Communications medicine · 2026Article
- Physical activity substitution: An overlooked constraint on energy expenditure during exercise and physical activity interventions.Diabetes, obesity & metabolism · 2025Article
- Influence of 8-week endurance training on resting energy expenditure and body composition in women.Physiological reports · 2025Article
- Compensatory Responses to Exercise Training As Barriers to Weight Loss: Changes in Energy Intake and Non-exercise Physical Activity.Current nutrition reports · 2023Review
- Perspective: Is the Response of Human Energy Expenditure to Increased Physical Activity Additive or Constrained?Advances in nutrition (Bethesda, Md.) · 2023Article
- Altered motivation states for physical activity and 'appetite' for movement as compensatory mechanisms limiting the efficacy of exercise training for weight loss.Frontiers in psychology · 2023Article
- The Effects of an Acute Bout of Aerobic or Resistance Exercise on Nonexercise Physical Activity.Exercise, sport & movement · 2023Article
- Compensatory effects of different exercise durations on non-exercise physical activity, appetite, and energy intake in normal weight and overweight adults.Frontiers in physiology · 2022Article
- Total energy expenditure (TEE) of young adults from urban South India: revisiting their daily energy requirement.European journal of clinical nutrition · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeThis study aimed to examine compensatory changes in nonexercise energy expenditure (NEEx) and nonexercise physical activity (NEPA) in response to an aerobic exercise training program.
methodsNinety-two overweight/obese (body mass index, 25-39.9 kg·m) sedentary young adults (18-30 yr) completed a 10-month randomized clinical efficacy trial of aerobic exercise 5 d·wk at either 400 kcal per session (n = 37), 600 kcal per session (n = 37), or control (n = 18). Total daily energy expenditure (TDEE) and resting metabolic rate (RMR) were measured at months 0 and 10. NEPA was measured by an accelerometer at months 0, 3.5, 7, and 10. NEEx was calculated by the following formula: [(total daily energy expenditure × 0.9) - RMR] - net EEEx (EEEx-RMR). Mixed modeling was used to examine differences between groups (group effect), within groups (time effect), and group-time interaction for NEEx and NEPA.
resultsWithin the exercise groups, there were no significant effects (all P > 0.05) of group, time, or group-time interaction for NEPA. In addition, there were no significant within- or between-group differences for change in NEEx. However, activity counts per minute were significantly higher (P < 0.001) in the 600-kcal-per-session group (346 ± 141 min·d) versus controls (290 ± 106 min·d) at month 7 and significantly higher (P < 0.001) in both the 600-kcal-per-session (345 ± 163 min·d) and 400-kcal-per-session groups (317 ± 146 min·d) versus controls (277 ± 116 min·d) at 10 months.
conclusionsA 10-month aerobic exercise training program in previously sedentary, overweight and obese young adults was not associated with compensatory decreases in NEEx or NEPA. Results suggest that overweight and obese individuals do not become less physically active or spend more time in sedentary pursuits in response to exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.