Evidence map›Paper›PMID 24694654›Full record

ReviewCurrent opinion in otolaryngology & head and neck surgery2014

The association of premorbid diseases with chronic rhinosinusitis with and without polyps.

Kent Lam, Annemarie G Hirsch, Bruce K Tan

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in otolaryngology & head and neck surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Risk of swallowing disorders in patients with chronic rhinosinusitis and nasal polyposis in comparison to healthy controls: a Survey of 50 cases.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Association ofAsia Pacific allergy · 2019
    Article
  8. Article
  9. Review
  10. Risk factors for chronic rhinosinusitis.Current opinion in allergy and clinical immunology · 2015
    Review
  11. Chronic Rhinosinusitis without Nasal Polyps.The journal of allergy and clinical immunology. In practice
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kent LamaDepartment of Otolaryngology - Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois bCenter for Health Research, Geisinger Health System, Danville, Pennsylvania, USA.
Annemarie G Hirsch
Bruce K Tan
Northwestern University · USGeisinger Health System · US

Funding

Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KERN, ROBERT C · 2014 to 2017
$7.9M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisP01AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2013 to 2013
$1.7M
Role for B-cell mediated olfactory loss in Chronic Sinusitis with Nasal PolypsK23DC012067 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAN, BRUCE K · 2012 to 2016
$1.1M
NIAID NIH HHS P01 AI106683NIAID NIH HHS U19 AI106683NIDCD NIH HHS K23 DC012067NIDCD NIH HHS K23DC012067
6 · The paper itself

Abstract

purpose of reviewTo review the recent insights regarding the epidemiology of adult chronic rhinosinusitis (CRS), with particular attention to its association with other premorbid conditions. Identifying premorbid disease associations establishes potential risk factors for developing CRS and helps corroborate current postulates of the various pathophysiologic mechanisms involved with the development and persistence of paranasal sinus inflammation. RECENT

findingsRecent findings demonstrate that the diagnosis of CRS is associated with a higher premorbid prevalence of upper airway diseases, lower airway diseases, gastroesophageal reflux disease, diseases of epithelial tissues, autoimmune disorders, and psychiatric conditions. Although some of these conditions have long been associated with CRS, improvements in study design and future studies in the general population will more accurately estimate the relative strengths of associations, clinical relevance, and temporal relationship of these various conditions in relation to the development of CRS. SUMMARY: The predisposing patterns of premorbid illnesses may provide valuable information regarding the underlying causes of CRS and allow for both therapeutic and preventive interventions. There remains conflicting evidence within the literature regarding the association of CRS with some medical conditions, signifying the need for continued research on the subject. Limitations of the current studies include small sample sizes, lack of prospective longitudinal or interventional studies that help establish causality, and variable criteria for diagnosis of CRS in the outpatient setting.

Indexed as

Autoimmune DiseasesChronic DiseaseDisease SusceptibilityGastroesophageal RefluxHumansMental DisordersNasal PolypsRhinitisSinusitis

Identifiers

PMID24694654
PMCPMC4089516
OpenAlexW2313139832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.