ReviewCurrent cardiology reviews2014
CTO pathophysiology: how does this affect management?
Review in Current cardiology reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of impaired renal function on outcomes of chronic total occlusion undergoing revascularization: a systemic review and meta-analysis.International urology and nephrology · 2022Pooled it
- Impact of the Presence of Chronic Total Occlusions on the Survival of Patients Treated with Coronary Artery Bypass Grafting.Journal of cardiovascular development and disease · 2025Article
- Retrograde Approach to Manage Acute Coronary Closure Due to Dissection.JACC. Case reports · 2025Article
- Debating the State-of-the-Art CTO PCI: Is There Still Room for Discussion?JACC. Case reports · 2023Article
- The value of quantitative plaque analysis based on coronary computed tomography angiography in predicting the percutaneous coronary intervention outcome of chronic total occlusion lesions.Quantitative imaging in medicine and surgery · 2023Article
- Predictors and prognosis of PCI-related myocardial injury in chronic total occlusion.BMC cardiovascular disorders · 2022Article
- A Novel Classification for Predicting Chronic Total Occlusion Percutaneous Coronary Intervention.Frontiers in cardiovascular medicine · 2022Article
- Reattempt Percutaneous Coronary Intervention of Chronic Total Occlusions after Prior Failures: A Single-Center Analysis of Strategies and Outcomes.Journal of interventional cardiology · 2021Article
- Sharp recanalization of peripheral arterial chronic total occlusions.The British journal of radiology · 2021Review
- Delayed spontaneous recanalization of chronic total occlusion of left anterior descending artery after attempted but failed revascularization during percutaneous coronary intervention.Journal of community hospital internal medicine perspectives · 2018Article
- Effect of Lesion Age on Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From a Contemporary US Multicenter Registry.The Canadian journal of cardiology · 2016Article
- Applied Pathology for Interventions of Coronary Chronic Total OcclusionCurrent cardiology reviews · 2015Article
- Coronary chronic total occlusion intervention: A pathophysiological perspective.Indian heart journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledChronic total occlusion (CTO) pathophysiology has been described in a few, small studies using post mortem histology, and more recently, in vivo intravascular ultrasound (IVUS) to analyse the constituents of occluded segments. Recent improvements in equipment and techniques have revealed new insights into physical characteristics of occluded coronaries, which in turn enable predictable procedural success. The purpose of this review is to consider the published evidence describing CTO pathophysiology from the perspective of the hybrid algorithm approach to CTO PCI.
methodsLiterature searches using "Chronic Occlusion", "angioplasty", and" pathology" as keywords. Further searches on "coronary" "collateral", "Viability". Bibliographies were scrutinised for further key publications in an iterative process. Papers describing animal models were excluded.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.