ReviewScandinavian journal of trauma, resuscitation and emergency medicine2014
Acute bronchiolitis in infants, a review.
Review in Scandinavian journal of trauma, resuscitation and emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 145 citations in OpenAlex.
- Children born preterm admitted to paediatric intensive care for bronchiolitis: a systematic review and meta-analysis.BMC pediatrics · 2023Pooled it
- Respiratory syncytial virus prophylaxis for prevention of recurrent childhood wheeze and asthma: a systematic review.Systematic reviews · 2020Pooled it
- Exploring the efficacy of using hypertonic saline for nebulizing treatment in children with bronchiolitis: a meta-analysis of randomized controlled trials.BMC pediatrics · 2020Pooled it
- Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children.The Cochrane database of systematic reviews · 2015Pooled it
- High flow nasal cannula therapy versus continuous positive airway pressure and nasal positive pressure ventilation in infants with severe bronchiolitis: a randomized controlled trial.The Pan African medical journal · 2021Trial
- Point-of-care lung ultrasound in infants with bronchiolitis in the pediatric emergency department: a prospective study.European journal of pediatrics · 2019Trial
- Trial
- The severity of acute bronchiolitis in infants was associated with quality of life nine months later.Acta paediatrica (Oslo, Norway : 1992) · 2016Trial
- Trial
- Review
- Incidence of Respiratory Syncytial Virus Infection Among Patients Aged Less Than 2 Years: A Retrospective Study From an Italian Southern Region in Years 2018-2023.Influenza and other respiratory viruses · 2026Observational
- Association of preterm birth with severity of molecularly-confirmed acute viral respiratory illness presenting to the emergency department: a multi-year analysis.Frontiers in pediatrics · 2026Article
- Bronchial hyper-reactivity in young adults after hospitalisation for bronchiolitis in infancy.BMJ open respiratory research · 2025Article
- Systemic IL-10 and IFN-γ Levels in Respiratory Syncytial Virus- and Rhinovirus-Infected Bulgarian Children with Acute Bronchiolitis and Their Impact on Clinical Manifestation.Pathogens (Basel, Switzerland) · 2025Article
- Severe bronchiolitis before and after the COVID-19 pandemic: a retrospective database analysis by the Italian Network of PICU study group (TIPNet).Journal of anesthesia, analgesia and critical care · 2024Article
- Review
- Timing of Neonatal Discharge and Unplanned Readmission to PICUs Among Infants Born Preterm.JAMA network open · 2024Article
- Trends in hospitalizations of children with respiratory syncytial virus aged less than 1 year in Italy, from 2015 to 2019.Italian journal of pediatrics · 2024Article
- Reduced Serum Brain-Derived Neurotrophic Factor in Infants Affected by Severe Bronchiolitis.Current neuropharmacology · 2024Article
- Epidemiology and risk factors of respiratory syncytial virus associated acute respiratory tract infection in hospitalized children younger than 5 years from Sri Lanka.Frontiers in microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute viral bronchiolitis is one of the most common medical emergency situations in infancy, and physicians caring for acutely ill children will regularly be faced with this condition. In this article we present a summary of the epidemiology, pathophysiology and diagnosis, and focus on guidelines for the treatment of bronchiolitis in infants. The cornerstones of the management of viral bronchiolitis are the administration of oxygen and appropriate fluid therapy, and overall a "minimal handling approach" is recommended. Inhaled adrenaline is commonly used in some countries, but the evidences are sparse. Recently, inhalation with hypertonic saline has been suggested as an optional treatment. When medical treatment fails to stabilize the infants, non-invasive and invasive ventilation may be necessary to prevent and support respiratory failure. It is important that relevant treatment algorithms exist, applicable to all levels of the treatment chain and reflecting local considerations and circumstances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.