ArticleAJOB neuroscience2013
Addiction: Current Criticism of the Brain Disease Paradigm.
Article in AJOB neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
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- Opioid quantification via microsampling techniques to assess opioid use in human laboratory studies.Scientific reports · 2025Article
- Examining the relationship between public stigma, models of addiction, and addictive disorders.Addiction research & theory · 2025Article
- Knowledge of medications for opioid use disorder and associated stigma among primary care professionals.Annals of medicine · 2024Article
- A survey of international addiction researchers' views on implications of brain-based explanations of addiction and the responsibility of affected persons.Nordisk alkohol- & narkotikatidskrift : NAT · 2024Article
- Media framings of the role of genomics in "addiction" in the United States from 2015 to 2019: Individualized risk, biomedical expertise, and the limits of destigmatization.Public understanding of science (Bristol, England) · 2024Article
- Grayken lessons: between a rock and a hard place? A 37-year-old man with acute liver injury while enrolled in a managed alcohol program for severe alcohol use disorder.Addiction science & clinical practice · 2023Article
- A comparative review on neuroethical issues in neuroscientific and neuroethical journals.Frontiers in neuroscience · 2023Review
- Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling.Frontiers in molecular neuroscience · 2023Review
- The Harms of Constructing Addiction as a Chronic, Relapsing Brain Disease.American journal of public health · 2022Article
- Getting "clean" from nonsuicidal self-injury: Experiences of addiction on the subreddit r/selfharm.Journal of behavioral addictions · 2022Article
- Not You: Addiction, Relapse, and Release in Uganda.Culture, medicine and psychiatry · 2022Article
- Reaching High: Translating Emergent Practices of Street-Level Drug Users to Institute Harm Reduction in Durban-Implications for Urban Governance.Urban forum (Johannesburg, South Africa) · 2022Article
- The Impact of Stigma on People with Opioid Use Disorder, Opioid Treatment, and Policy.Substance abuse and rehabilitation · 2022Review
- What is a mental disorder? An exemplar-focused approach.Psychological medicine · 2021Review
- "I Was Raised in Addiction": Constructions of the Self and the Other in Discourses of Addiction and Recovery.Qualitative health research · 2020Article
- Buprenorphine dispensing in an epicenter of the U.S. opioid epidemic: A case study of the rural risk environment in Appalachian Kentucky.The International journal on drug policy · 2020Article
- Addiction Mindsets and Psychological Processes of Quitting Smoking.Substance use & misuse · 2019Article
- Free Will and the Brain Disease Model of Addiction: The Not So Seductive Allure of Neuroscience and Its Modest Impact on the Attribution of Free Will to People with an Addiction.Frontiers in psychology · 2017Article
- Q: Is Addiction a Brain Disease or a Moral Failing? A: Neither.Neuroethics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
Abstract
To deepen understanding of efforts to consider addiction a "brain disease," we review critical appraisals of the disease model in conjunction with responses from in-depth semistructured stakeholder interviews with (1) patients in treatment for addiction and (2) addiction scientists. Sixty-three patients (from five alcohol and/or nicotine treatment centers in the Midwest) and 20 addiction scientists (representing genetic, molecular, behavioral, and epidemiologic research) were asked to describe their understanding of addiction, including whether they considered addiction to be a disease. To examine the NIDA brain disease paradigm, our approach includes a review of current criticism from the literature, enhanced by the voices of key stakeholders. Many argue that framing addiction as a disease will enhance therapeutic outcomes and allay moral stigma. We conclude that it is not necessary, and may be harmful, to frame addiction as a disease.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.