Evidence map›Paper›PMID 24693296›Full record

ArticleIranian journal of radiology : a quarterly journal published by the Iranian Radiological Society2014

Early ultrasound assessment of renal transplantation as the valuable biomarker of long lasting graft survival: a cross-sectional study.

Ahmad Enhesari, Saeid Mardpour, Zohreh Makki, Soura Mardpour

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Article in Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Ahmad EnhesariDepartment of Radiology, Faculty of Medicine and Health Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Saeid MardpourDepartment of Radiology, Faculty of Medicine and Health Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Zohreh MakkiDepartment of Radiology, Faculty of Medicine and Health Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Soura MardpourApplied Cell Sciences Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, there has been little agreement on the use of ultrasonographic parameters in predicting the long-term outcome after transplantation. This study evaluates whether ultrasonography of the graft performed in the early stage after transplantation is a valuable predictor for long-term-outcome.

objectivesThe aim of this study was to evaluate the association of ultrasonographic parameters (resistive index [RI], pulsatility index[PI], end diastolic velocity [EDV], graft length and graft parenchymal volume) measured within the first week after transplantation with 6 months graft function. PATIENTS AND

methodsA cross-sectional study was performed on 91 (46 males and 45 females) living renal transplants between April 2011 and February 2013. All patients underwent an ultrasonography at the first week after transplantation. Intrarenal Doppler indices including RI, PI and EDV were measured at the interlobar artery level and the graft length and parenchymal volume were defined with gray scale ultrasonography. Graft function was estimated at 6months by glomerular filtration rate (GFR). Unpaired t-test and multivariate-linear and logistic regression analysis were used to estimate the relationship between ultrasonographic parameters and GFR.

resultsFourteen patients (15.4%) had impaired graft function after 6 months (GFR less than 60 ml/min/1.73m2). Multivariate linear regression analysis showed significant correlation between GFR at 6 months and RI, PI and EDV with a P value of 0.026, 0.016 and 0.015, respectively. Logistic regression analysis showed that GFR<60 ml/min/1.73 m2 at 6 months was significantly associated with RI>0.7 (odds ratio=2.20, P value=0.004) and PI>1.3 (odds ratio=2.74, P value<0.001) and EDV<9 cm/Sec (odds ratio=1.83, P value=0.03).

conclusionsIn this study, kidney transplant recipients with a lower RI and PI and a higher EDV at 1week showed better graft function at 6 months after transplantation.

Indexed as

Glomerular Filtration RateKidney TransplantationUltrasonography

Identifiers

PMID24693296
PMCPMC3955852

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