ReviewGastroenterology research and practice2014
Gluten sensitivity presenting as a neuropsychiatric disorder.
Review in Gastroenterology research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Metal Dyshomeostasis as a Driver of Gut Pathology in Autism Spectrum Disorders.Journal of neurochemistry · 2025Pooled it
- Pooled it
- Use of a Gluten-Free Diet in Schizophrenia: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Are therapeutic diets an emerging additional choice in autism spectrum disorder management?World journal of pediatrics : WJP · 2018Pooled it
- Psychiatric Symptoms Associated with Non-Celiac Gluten Sensitivity: A Focused Narrative Review.Nutrients · 2026Review
- Gluten and its relationship with inflammation and Parkinson's Disease: A literature review.AIMS neuroscience · 2025Review
- Investigating the Impacts of Diet, Supplementation, Microbiota, Gut-Brain Axis on Schizophrenia: A Narrative Review.Nutrients · 2024Review
- Recurrent Psychosis in Non-celiac Gluten Sensitivity.Journal of community hospital internal medicine perspectives · 2023Article
- Review
- Clinical characteristics and sociodemographic features of psychotic major depression.Annals of general psychiatry · 2021Article
- Microbiome and Mental Health, Specifically as It Relates to Adolescents.Current psychiatry reports · 2019Review
- An exploration into the motivation for gluten avoidance in the absence of coeliac disease.Gastroenterology and hepatology from bed to bench · 2018Article
- Shared and unique common genetic determinants between pediatric and adult celiac disease.BMC medical genomics · 2016Article
- Bread and Other Edible Agents of Mental Disease.Frontiers in human neuroscience · 2016Review
- Integrative Medicine Approach to Pediatric Obsessive-Compulsive Disorder and Anxiety: A Case Report.Global advances in health and medicine · 2016Article
- Gluten Psychosis: Confirmation of a New Clinical Entity.Nutrients · 2015Article
- Article
- Clinical and diagnostic aspects of gluten related disorders.World journal of clinical cases · 2015Review
- Assessing of Celiac Disease and Nonceliac Gluten Sensitivity.Gastroenterology research and practice · 2015Review
- Zinc in gut-brain interaction in autism and neurological disorders.Neural plasticity · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been increasing recognition in the medical community and the general public of the widespread prevalence of gluten sensitivity. Celiac disease (CD) was initially believed to be the sole source of this phenomenon. Signs and symptoms indicative of nonceliac gluten sensitivity (NCGS), in which classical serum and intestinal findings of CD may be absent, have been frequently reported of late. Clinical manifestations in patients with NCGS are characteristically triggered by gluten and are ameliorated or resolved within days to weeks of commencing a gluten-free diet. Emerging scientific literature contains several reports linking gluten sensitivity states with neuropsychiatric manifestations including autism, schizophrenia, and ataxia. A clinical review of gluten sensitivity is presented alongside a case illustrating the life-changing difference achieved by gluten elimination in a patient with a longstanding history of auditory and visual hallucinations. Physicians in clinical practice should routinely consider sensitivity issues as an etiological determinant of otherwise inexplicable symptoms. Pathophysiologic mechanisms to explain the multisystem symptomatology with gluten sensitivity are considered.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.