ArticleHuman brain mapping2014
Distinct fine-scale fMRI activation patterns of contra- and ipsilateral somatosensory areas 3b and 1 in humans.
Article in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- Optimal location for gesture decoding in the sensorimotor cortex and implications for brain-computer interface research.NeuroImage · 2026Article
- Nonlinear Asymmetric Blood Oxygenation Level Dependent Responses in Somatosensory Cortex.Human brain mapping · 2026Article
- Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research.Neuropsychiatric disease and treatment · 2025Review
- The 3D Structural Architecture of the Human Hand Area Is Nontopographic.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- In the back of your mind: Cortical mapping of paraspinal afferent inputs.Human brain mapping · 2022Article
- Aura Mapping: Where Vision and Somatosensation Meet.Vision (Basel, Switzerland) · 2021Article
- A touch of hierarchy: population receptive fields reveal fingertip integration in Brodmann areas in human primary somatosensory cortex.Brain structure & function · 2021Article
- The organizational principles of de-differentiated topographic maps in somatosensory cortex.eLife · 2021Article
- Relation between palm and finger cortical representations in primary somatosensory cortex: A 7T fMRI study.Human brain mapping · 2021Article
- Different activation signatures in the primary sensorimotor and higher-level regions for haptic three-dimensional curved surface exploration.NeuroImage · 2021Article
- Fine-Grained Mapping of Cortical Somatotopies in Chronic Complex Regional Pain Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Visually-Driven Maps in Area 3b.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Review of functional and clinical relevance of intrinsic signal optical imaging in human brain mapping.Neurophotonics · 2017Review
- Article
- Asymmetric Functional Connectivity of the Contra- and Ipsilateral Secondary Somatosensory Cortex during Tactile Object Recognition.Frontiers in human neuroscience · 2017Article
- Investigating the Stability of Fine-Grain Digit Somatotopy in Individual Human Participants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Tactile representation of the head and shoulders assessed by fMRI in the nonhuman primate.Journal of neurophysiology · 2016Article
- On the bimanual integration of proprioceptive information.Experimental brain research · 2015Article
- Article
- Functional connectivity of primary motor cortex is dependent on genetic burden in prodromal Huntington disease.Brain connectivity · 2014Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Inter-areal and ipsilateral cortical responses to tactile stimulation have not been well described in human S1 cortex. By taking advantage of the high signal-to-noise ratio at 7 T, we quantified blood oxygenation level dependent (BOLD) response patterns and time courses to tactile stimuli on individual distal finger pads at a fine spatial scale, and examined whether there are inter-areal (area 3b versus area 1) and interhemispheric response differences to unilateral tactile stimulation in healthy human subjects. We found that 2-Hz tactile stimulation of individual fingertips evoked detectable BOLD signal changes in both contralateral and ipsilateral area 3b and area 1. Contralateral digit activations were organized in an orderly somatotopic manner, and BOLD responses in area 3b were more digit selective than those in area 1. However, the area of cortex that was responsive to stimulation of a single digit (stimulus-response field) was similar across areas. In the ipsilateral hemisphere, response magnitudes in both areas 3b and 1 were significantly weaker than those of the contralateral hemisphere. Digit activations exhibited no clear somatotopic organizational pattern in either area 3b or area 1, yet digit selectivity was retained in area 1 but not in area 3b. The observation of distinct digit-selective responses of contralateral area 3b versus area 1 supports a higher order function of contralateral area 1 in spatial integration. In contrast, ipsilateral cortices may play a less discriminative role in the perception of unilateral tactile sensation in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.