ArticleInvestigative ophthalmology & visual science2014
Tear film interferometry and corneal surface roughness.
Article in Investigative ophthalmology & visual science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Real-time OCT feedback-controlled RPE photodisruption in ex vivo porcine eyes using 8 microsecond laser pulses.Biomedical optics express · 2023Article
- How Can We Best Diagnose Severity Levels of Dry Eye Disease: Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Evaluation of dry eye and Meibomian gland dysfunction in female androgenetic alopecia patients.International ophthalmology · 2021Article
- Changes in Corneal Epithelial Thickness Induced by Topical Antiglaucoma Medications.Journal of clinical medicine · 2021Article
- Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior During the Inter-Blink Period and Visual Fixation.Journal of clinical medicine · 2020Review
- In vivo thickness measurement of the lipid layer and the overall tear film by interferometry.Optics letters · 2019Article
- Characterization of the thickness of the tear film lipid layer using high resolution microscopy.The ocular surface · 2019Review
- Mechanisms, imaging and structure of tear film breakup.The ocular surface · 2018Review
- TFOS DEWS II Tear Film Report.The ocular surface · 2017Review
- Dysfunctional tear syndrome: dry eye disease and associated tear film disorders - new strategies for diagnosis and treatment.Current opinion in ophthalmology · 2017Review
- Association Between Serum Levels of Testosterone and Estradiol With Meibomian Gland Assessments in Postmenopausal Women.Investigative ophthalmology & visual science · 2016Article
- Dynamics and function of the tear film in relation to the blink cycle.Progress in retinal and eye research · 2015Review
- THz and mm-Wave Sensing of Corneal Tissue Water Content: Electromagnetic Modeling and Analysis.IEEE transactions on terahertz science and technology · 2015Article
- Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory.Biomedical optics express · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposePrevious studies of optical interference from the whole thickness of the precorneal tear film showed much lower contrast than from the pre-contact lens tear film. It is hypothesized that the recorded low contrast is related to roughness of the corneal surface compared with the smooth contact lens surface. This hypothesis is tested, and characteristics of this roughness are studied.
methodsReflectance spectra were recorded from 20 healthy individuals using a silicon-based sensor used in previous studies (wavelength range, 562-1030 nm) and an indium-gallium-arsenide (InGaAs) sensor responding at longer wavelengths (912-1712 nm). Interference from the whole thickness of the precorneal tear film caused oscillations in the reflectance spectra.
resultsSpectral oscillations recorded with the InGaAs sensor were found to decay as a Gaussian function of wave number (1/wavelength). This is consistent with a rough corneal surface, whose distribution of surface height is also a Gaussian function. Contrast of spectral oscillations for the InGaAs sensor was, on average, approximately four times greater than that for the silicon sensor.
conclusionsFor the Gaussian roughness model based on InGaAs spectra, the corneal surface was characterized by a surface height SD of 0.129 μm. Spectral oscillations recorded with a silicon-based camera can have higher contrast than expected from this Gaussian roughness model, indicating some reflectance from a smoother or more compact surface. The results also indicate that InGaAs cameras could provide whole-thickness interference images of higher contrast than silicon-based cameras.
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