ArticleNature cell biology2014
Understanding tissue context influences on intratumour heterogeneity.
Article in Nature cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: involvement of GADD45α, integrin-α5, -β5, -β1, and autophagy.Drug delivery and translational research · 2022Article
- Ordered micropattern arrays fabricated by lung-derived dECM hydrogels for chemotherapeutic drug screening.Materials today. Bio · 2022Article
- Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening.Scientific reports · 2021Article
- Biliary tract cancer patient-derived xenografts: Surgeon impact on individualized medicine.JHEP reports : innovation in hepatology · 2020Article
- Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue.Bulletin of mathematical biology · 2019Article
- Steps in Mechanotransduction Pathways that Control Cell Morphology.Annual review of physiology · 2019Review
- From Chemotherapy to Combined Targeted Therapeutics:Frontiers in pharmacology · 2018Review
- Human colorectal cancer progression correlates with LOX-induced ECM stiffening.International journal of biological sciences · 2017Article
- Cancer stem cells and early stage basal-like breast cancer.World journal of obstetrics and gynecology · 2016Article
- Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening.Oncotarget · 2015Article
- Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts.Cancer research · 2015Review
- The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface.International journal of nanomedicine · 2015Article
- Evolving concepts of tumor heterogeneity.Cell & bioscience · 2014Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Although human cancers exhibit intratumour heterogeneity, the influence of the tumour environment on this property is unclear. Single basal-like mammary epithelial cells are now shown to engage a dynamic TGFBR3-JUND signalling circuit in an extracellular-matrix-dependent manner. Cell transition between the distinct gene expression states underlying this circuit alters their properties and may modulate their propensity to malignancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.