Evidence map›Paper›PMID 24691165›Full record

ReviewBioengineered

Biotechnological production of value-added carotenoids from microalgae: Emerging technology and prospects.

Kristine Wichuk, Sigurður Brynjólfsson, Weiqi Fu

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineered. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kristine WichukCenter for Systems Biology; University of Iceland; Reykjavík, Iceland.
Sigurður BrynjólfssonCenter for Systems Biology; University of Iceland; Reykjavík, Iceland; Faculty of Industrial Engineering, Mechanical Engineering, and Computer Science; University of Iceland; Reykjavík, Iceland.
Weiqi FuCenter for Systems Biology; University of Iceland; Reykjavík, Iceland.
University of Iceland · ISCenter for Systems Biology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently evaluated the relationship between abiotic environmental stresses and lutein biosynthesis in the green microalga Dunaliella salina and suggested a rational design of stress-driven adaptive evolution experiments for carotenoids production in microalgae. Here, we summarize our recent findings regarding the biotechnological production of carotenoids from microalgae and outline emerging technology in this field. Carotenoid metabolic pathways are characterized in several representative algal species as they pave the way for biotechnology development. The adaptive evolution strategy is highlighted in connection with enhanced growth rate and carotenoid metabolism. In addition, available genetic modification tools are described, with emphasis on model species. A brief discussion on the role of lights as limiting factors in carotenoid production in microalgae is also included. Overall, our analysis suggests that light-driven metabolism and the photosynthetic efficiency of microalgae in photobioreactors are the main bottlenecks in enhancing biotechnological potential of carotenoid production from microalgae.

Indexed as

Adaptation, PhysiologicalBioreactorsCarotenoidsChlorophytaLightMetabolic EngineeringMetabolic Networks and PathwaysMicroalgaePhotosynthesisCarotenoidsadaptive laboratory evolutioncarotenoid metabolismDunaliella salinaenvironmental stressLED-based photobioreactorsmicroalgae

Identifiers

PMID24691165
PMCPMC4101014
OpenAlexW2332753076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.