ArticleOptics letters2014
Tomographic lifetime imaging using combined early- and late-arriving photons.
Article in Optics letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Reconstruction of fluorophore absorption and fluorescence lifetime using early photon mesoscopic fluorescence molecular tomography: a phantom study.Journal of biomedical optics · 2022Article
- Comparison of fluorescence lifetime and multispectral imaging for quantitative multiplexing in biological tissue.Biomedical optics express · 2022Article
- The Resolution Matrix in Tomographic Multiplexing: Optimization of Inter-Parameter Cross-Talk, Relative Quantitation, and Localization.IEEE transactions on bio-medical engineering · 2019Article
- Comparison of tomographic fluorescence spectral and lifetime multiplexing.Optics letters · 2016Article
- All Photons Imaging Through Volumetric Scattering.Scientific reports · 2016Article
- Nonlinear greedy sparsity-constrained algorithm for direct reconstruction of fluorescence molecular lifetime tomography.Biomedical optics express · 2016Article
- Optimal estimator for tomographic fluorescence lifetime multiplexing.Optics letters · 2016Article
- Multiplexed fluorescence tomography with spectral and temporal data: demixing with intrinsic regularization.Biomedical optics express · 2016Article
- Fast single photon avalanche photodiode-based time-resolved diffuse optical tomography scanner.Biomedical optics express · 2015Article
- In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast.Cancer research · 2015Article
- Preclinical whole body time domain fluorescence lifetime multiplexing of fluorescent proteins.Journal of biomedical optics · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We present a novel, hybrid approach for time domain fluorescence tomography that efficiently combines lifetime multiplexing using late-arriving or asymptotic photons, with the high spatial resolution capability of early photon tomography. We also show that a decay amplitude-based asymptotic approach is superior to direct inversion of late-arriving photons for tomographic lifetime imaging within turbid media. The hybrid reconstruction approach is experimentally shown to recover fluorescent inclusions separated as close as 1.4 mm, with improved resolution and reduced cross talk compared to just using early photons or the asymptotic approach alone.
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Registered trials
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