Evidence map›Paper›PMID 24690608›Full record

ArticleJournal of veterinary science2014

Induction of antibody and interferon-γ production in mice immunized with virus-like particles of swine hepatitis E virus.

Young-Jo Song, Woo-Jung Park, Seul-Kee Lee, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Kun-Ho Seo, Young-Sun Kang, Jae-Young Song and 1 more

Abstract read
In one paragraph

Article in Journal of veterinary science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Young-Jo SongDepartment of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea.
Woo-Jung Park
Seul-Kee Lee
Joong-Bok Lee
Seung-Yong Park
Chang-Seon Song
Sang-Won Lee
Kun-Ho Seo
Young-Sun Kang
Jae-Young Song
In-Soo Choi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus-like particles (VLPs) composed of the truncated capsid protein of swine hepatitis E virus (HEV) were developed and immune responses of mice immunized with the VLPs were evaluated. IgG titers specific for the capsid protein of swine HEV were significantly higher for all groups of mice immunized with the VLPs than those of the negative control mice. Splenocytes from mice immunized with the VLPs also produced significantly greater quantities of interferon (IFN)-γ than interleukin (IL)-4 and IL-10. These newly developed swine HEV VLPs have the capacity to induce antigen-specific antibody and IFN-γ production in immunized mice.

Indexed as

AnimalsAntibodies, ViralCapsid ProteinsFemaleHepatitis EHepatitis E virusImmunizationInterferon-gammaMiceMice, Inbred BALB CSwineSwine DiseasesVaccines, Virus-Like ParticleViral Hepatitis VaccinesAntibodies, ViralCapsid ProteinsInterferon-gammaVaccines, Virus-Like ParticleViral Hepatitis Vaccinesinterferon-γswine hepatitis E virusvirus-like particle

Identifiers

PMID24690608
PMCPMC4269602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.