Evidence map›Paper›PMID 24690267›Full record

Trial reportImplementation science : IS2014

Did a quality improvement collaborative make stroke care better? A cluster randomized trial.

Maxine Power, Pippa J Tyrrell, Anthony G Rudd, Mary P Tully, David Dalton, Martin Marshall, Ian Chappell, Delphine Corgié, Don Goldmann, Dale Webb and 2 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Implementation science : IS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
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  9. Article
  10. The role of QI collaboratives in neonatology.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Audit as a Tool for Improving the Quality of Stroke Care: A Review.International journal of environmental research and public health · 2023
    Review
  16. Article
  17. Article
  18. Quality Improvement in Stroke Rehabilitation: A Scoping Review.Journal of multidisciplinary healthcare · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maxine PowerDirector of Innovation and Improvement Science, Salford Royal NHS Foundation Trust, Stott Lane, Salford, M6 8HD, England. maxine.power@nhs.net.
Pippa J Tyrrell
Anthony G Rudd
Mary P Tully
David Dalton
Martin Marshall
Ian Chappell
Delphine Corgié
Don Goldmann
Dale Webb
Mary Dixon-Woods
Gareth Parry

Funding

Wellcome Trust 097899
6 · The paper itself

Abstract

backgroundStroke can result in death and long-term disability. Fast and high-quality care can reduce the impact of stroke, but UK national audit data has demonstrated variability in compliance with recommended processes of care. Though quality improvement collaboratives (QICs) are widely used, whether a QIC could improve reliability of stroke care was unknown.

methodsTwenty-four NHS hospitals in the Northwest of England were randomly allocated to participate either in Stroke 90:10, a QIC based on the Breakthrough Series (BTS) model, or to a control group giving normal care. The QIC focused on nine processes of quality care for stroke already used in the national stroke audit. The nine processes were grouped into two distinct care bundles: one relating to early hours care and one relating to rehabilitation following stroke. Using an interrupted time series design and difference-in-difference analysis, we aimed to determine whether hospitals participating in the QIC improved more than the control group on bundle compliance.

resultsData were available from nine interventions (3,533 patients) and nine control hospitals (3,059 patients). Hospitals in the QIC showed a modest improvement from baseline in the odds of average compliance equivalent to a relative improvement of 10.9% (95% CI 1.3%, 20.6%) in the Early Hours Bundle and 11.2% (95% CI 1.4%, 21.5%) in the Rehabilitation Bundle. Secondary analysis suggested that some specific processes were more sensitive to an intervention effect.

conclusionsSome aspects of stroke care improved during the QIC, but the effects of the QIC were modest and further improvement is needed. The extent to which a BTS QIC can improve quality of stroke care remains uncertain. Some aspects of care may respond better to collaboratives than others.

trial registrationISRCTN13893902.

Indexed as

Cooperative BehaviorEnglandFemaleHumansMaleQuality ImprovementQuality of Health CareReproducibility of ResultsRisk FactorsStrokeStroke RehabilitationTime FactorsTreatment Outcome

Identifiers

PMID24690267
PMCPMC3997843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.