ArticleThe Review of scientific instruments2014
Synchronous digitization for high dynamic range lock-in amplification in beam-scanning microscopy.
Article in The Review of scientific instruments, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Removing crosstalk signals in neuron activity by time multiplexed excitations in a two-photon all-optical physiology system.Biomedical optics express · 2024Article
- Nanosecond-resolution photothermal dynamic imaging via MHZ digitization and match filtering.Nature communications · 2021Article
- Spatiotemporal monitoring of changes in oxy/deoxy-hemoglobin concentration and blood pulsation on human skin using smartphone-enabled remote multispectral photoplethysmography.Biomedical optics express · 2021Article
- Anomalous Diffusion Characterization by Fourier Transform-FRAP with Patterned Illumination.Biophysical journal · 2020Article
- Imaging the Nonlinear Susceptibility Tensor of Collagen by Nonlinear Optical Stokes Ellipsometry.Biophysical journal · 2016Article
- Second harmonic generation correlation spectroscopy for characterizing translationally diffusing protein nanocrystals.Acta crystallographica. Section D, Structural biology · 2016Article
- Guiding synchrotron X-ray diffraction by multimodal video-rate protein crystal imaging.Journal of synchrotron radiation · 2016Article
- Parts per Million Powder X-ray Diffraction.Analytical chemistry · 2015Article
- Synchronous-digitization for Video Rate Polarization Modulated Beam Scanning Second Harmonic Generation Microscopy.Proceedings of SPIE--the International Society for Optical Engineering · 2015Article
- Multi-channel beam-scanning imaging at kHz frame rates by Lissajous trajectory microscopy.Proceedings of SPIE--the International Society for Optical Engineering · 2015Article
- High frame-rate multichannel beam-scanning microscopy based on Lissajous trajectories.Optics express · 2014Article
- Polarization-modulated second harmonic generation ellipsometric microscopy at video rate.Analytical chemistry · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Digital lock-in amplification (LIA) with synchronous digitization (SD) is shown to provide significant signal to noise (S/N) and linear dynamic range advantages in beam-scanning microscopy measurements using pulsed laser sources. Direct comparisons between SD-LIA and conventional LIA in homodyne second harmonic generation measurements resulted in S/N enhancements consistent with theoretical models. SD-LIA provided notably larger S/N enhancements in the limit of low light intensities, through the smooth transition between photon counting and signal averaging developed in previous work. Rapid beam scanning instrumentation with up to video rate acquisition speeds minimized photo-induced sample damage. The corresponding increased allowance for higher laser power without sample damage is advantageous for increasing the observed signal content.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.