Evidence map›Paper›PMID 24689051›Full record

ArticleBioMed research international2014

Mycobacterium avium Subsp. avium infection in four veal calves: differentiation from intestinal tuberculosis.

Christine Goepfert, Nadine Regenscheit, Vanessa Schumacher, Simone Roos, Christophe Rossier, Corinne Baehler, Sarah Schmitt, Horst Posthaus

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Identification and Phylogenetic Analysis ofTransboundary and emerging diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christine GoepfertInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.ORCID 0000-0003-3052-8802
Nadine RegenscheitInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.ORCID 0000-0003-4089-2026
Vanessa SchumacherInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.ORCID 0000-0003-4882-9881
Simone RoosInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.ORCID 0000-0001-5849-3790
Christophe RossierInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.
Corinne BaehlerKaelberpraxis, 6221 Rickenbach, Switzerland.
Sarah SchmittInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Horst PosthausInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Länggassstraße 122, 3012 Bern, Switzerland.ORCID 0000-0002-4579-7493
University of Bern · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium avium subsp. avium (Maa) is an intracellular pathogen belonging to the Mycobacterium avium-intracellulare complex (MAC). Reservoirs of MAC are the natural environment, wildlife and domestic animals. In adult bovine, MAC infections are typically caused by Mycobacterium avium subsp. paratuberculosis (Map). Maa infections in bovine are rarely reported but may cause clinical disease and pathological lesions similar to those observed in paratuberculosis or those induced by members of the Mycobacterium tuberculosis complex (MTBC). Therefore, differentiation of MAC from MTBC infection should be attempted, especially if unusual mycobacterial lesions are encountered. Four veal calves from a fattening farm dying with clinical signs of otitis media, fever, and weight loss were submitted for necropsy. Samples from affected organs were taken for histologic investigation, bacteriologic culture, and bacterial specification using PCR. Macroscopic thickening of the intestinal mucosa was induced by granulomatous enteritis and colitis. Intracytoplasmic acid-fast bacteria were detected by Ziehl-Neelsen stains and PCR revealed positive results for Mycobacterium avium subsp. avium. Clinical and pathological changes of Maa infection in veal calves had features of Mycobacterium avium subsp. paratuberculosis and the MTBC. Therefore, Mycobacterium tuberculosis complex infection should be considered in cases of granulomatous enteritis in calves.

Indexed as

AnimalsCattleDiagnosis, DifferentialIntestinesLymph NodesMycobacterium aviumPolymerase Chain ReactionTuberculosis, Gastrointestinal

Identifiers

PMID24689051
PMCPMC3943398
OpenAlexW2003178499

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.