Evidence map›Paper›PMID 24688822›Full record

ArticleBiomedical optics express2014

Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples.

Marjan Razani, Timothy W H Luk, Adrian Mariampillai, Peter Siegler, Tim-Rasmus Kiehl, Michael C Kolios, Victor X D Yang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marjan RazaniDepartment of Physics, Ryerson University, Toronto, Canada.
Timothy W H LukDepartment of Electrical and Computer Engineering, Ryerson University, Toronto, Canada.
Adrian MariampillaiDepartment of Electrical and Computer Engineering, Ryerson University, Toronto, Canada.
Peter SieglerDepartment of Electrical and Computer Engineering, Ryerson University, Toronto, Canada.
Tim-Rasmus KiehlDepartment of Pathology, University Health Network, Toronto, Ontario Canada ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.
Michael C KoliosDepartment of Physics, Ryerson University, Toronto, Canada ; mkolios@ryerson.ca.
Victor X D YangDepartment of Physics, Ryerson University, Toronto, Canada ; Department of Electrical and Computer Engineering, Ryerson University, Toronto, Canada ; Division of Neurosurgery, University of Toronto, Toronto, Canada.
Toronto Metropolitan University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we explored the potential of measuring shear wave propagation using optical coherence elastography (OCE) in an inhomogeneous phantom and carotid artery samples based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 μs duration, applying acoustic radiation force (ARF) to inhomogeneous phantoms and carotid artery samples, synchronized with a swept-source OCT (SS-OCT) imaging system. The phantoms were composed of gelatin and titanium dioxide whereas the carotid artery samples were embedded in gel. Differential OCT phase maps, measured with and without the ARF, detected the microscopic displacement generated by shear wave propagation in these phantoms and samples of different stiffness. We present the technique for calculating tissue mechanical properties by propagating shear waves in inhomogeneous tissue equivalent phantoms and carotid artery samples using the ARF of an ultrasound transducer, and measuring the shear wave speed and its associated properties in the different layers with OCT phase maps. This method lays the foundation for future in-vitro and in-vivo studies of mechanical property measurements of biological tissues such as vascular tissues, where normal and pathological structures may exhibit significant contrast in the shear modulus.

Indexed as

(170.4500) Optical coherence tomography(170.6935) Tissue characterization

Identifiers

PMID24688822
PMCPMC3959849
OpenAlexW2008765675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.