ReviewComputational and structural biotechnology journal2012
Developing a yeast cell factory for the production of terpenoids.
Review in Computational and structural biotechnology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 69 citations in OpenAlex.
- Metabolic Engineering of Terpenoid Biosynthesis in Medicinal Plants: From Genomic Insights to Biotechnological Applications.Current issues in molecular biology · 2025Review
- Chemical and transcriptomic analyses of leaf trichomes from Cistus creticus subsp. creticus reveal the biosynthetic pathways of certain labdane-type diterpenoids and their acetylated forms.Journal of experimental botany · 2024Article
- Engineering a carbon source-responsive promoter for improved biosynthesis in the non-conventional yeastMetabolic engineering communications · 2024Article
- Iterative gene integration mediated by 26S rDNA and non-homologous end joining for the efficient production of lycopene in Yarrowia lipolytica.Bioresources and bioprocessing · 2023Article
- MULTI-SCULPT: Multiplex Integration via Selective, CRISPR-Mediated, Ultralong Pathway Transformation in Yeast for Plant Natural Product Synthesis.ACS synthetic biology · 2022Article
- Screening Wild Yeast Isolated from Cocoa Bean Fermentation Using Volatile Compounds Profile.Molecules (Basel, Switzerland) · 2022Article
- Characteristics of NtCCD1-3 from tobacco, and protein engineering of the CCD1 to enhanceFrontiers in microbiology · 2022Article
- Systematic mining of fungal chimeric terpene synthases using an efficient precursor-providing yeast chassis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Real-Time Monitoring of the Yeast Intracellular State During Bioprocesses With a Toolbox of Biosensors.Frontiers in microbiology · 2021Article
- The Model SystemLife (Basel, Switzerland) · 2020Review
- Article
- EngineeringFrontiers in bioengineering and biotechnology · 2020Article
- Plant terpenes that mediate below-ground interactions: prospects for bioengineering terpenoids for plant protection.Pest management science · 2019Review
- Co-production of microbial oil and exopolysaccharide by the oleaginous yeastRSC advances · 2018Article
- Synthesis and techno-economic assessment of microbial-based processes for terpenes production.Biotechnology for biofuels · 2018Article
- Engineering tolerance to industrially relevant stress factors in yeast cell factories.FEMS yeast research · 2017Review
- Article
- Cellular factories for coenzyme QMicrobial cell factories · 2017Review
- Characterization of an evolved carotenoids hyper-producer of Saccharomyces cerevisiae through bioreactor parameter optimization and Raman spectroscopy.Journal of industrial microbiology & biotechnology · 2016Article
- Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production.Microbial cell factories · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Technological developments over the past century have made microbes the work-horses of large scale industrial production processes. Current efforts focus on the metabolic engineering of microbial strains to produce high levels of desirable end-products. The arsenal of the contemporary metabolic engineer contains tools that allow either targeted rational interventions or global screens that combine classical approaches with -omics technologies. Production of terpenoids in S. cerevisiae presents a characteristic example of contemporary biotechnology that integrates all the variety of novel approaches used in metabolic engineering. Terpenoids have attracted significant interest as pharmaceuticals, flavour and fragrance additives, and, more recently, biofuels. The ongoing metabolic engineering efforts, combined with the continuously increasing number of terpene biosynthetic enzymes discovered will enable the economical and environmentally friendly production of a wide range of compounds.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.