Evidence map›Paper›PMID 24688607›Full record

ArticleReviews in infection2010

Regulation of host innate immunity by hepatitis C virus: crosstalk between hepatocyte and NK/DC.

Sung-Jae Park, Young S Hahn

Abstract read
In one paragraph

Article in Reviews in infection, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sung-Jae ParkBeirne B Carter Center for Immunology Research, University of Virginia, Charlottesville, VA 22908, USA ; Department of Internal Medicine, College of Medicine, Inje University, Busan, Korea.
Young S HahnBeirne B Carter Center for Immunology Research, University of Virginia, Charlottesville, VA 22908, USA ; Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA ; Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA.

Funding

Suppression of HCV-specific CD4+ T Cells by Core ProteinU19AI066328 · NIAID · UNIVERSITY OF COLORADO DENVER · PI ROSEN, HUGO RAMON · 2005 to 2014
$6.8M
Role of HCV in aberrant APC activation/functionR01AI098126 · NIAID · UNIVERSITY OF VIRGINIA · PI HAHN, YOUNG S. · 2012 to 2016
$1.9M
Impaired T cell function by HCV coreR01DK066754 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI HAHN, YOUNG S. · 2004 to 2008
$1.5M
NIAID NIH HHS R01 AI098126NIAID NIH HHS U19 AI066328NIDDK NIH HHS R01 DK066754
6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection in humans is remarkably efficient in establishing viral persistence, leading to the development of liver cirrhosis and hepatocellular carcinoma. CD8

Indexed as

DCevasion of TLR signalinginnate immunitythe impaired function of NKTLR activation

Identifiers

PMID24688607
PMCPMC3969740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.