Evidence map›Paper›PMID 24688498›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2013

Cashew apple juice as microbial cultivation medium for non-immunogenic hyaluronic acid production.

Adriano H Oliveira, Cristiane C Ogrodowski, André C de Macedo, Maria Helena A Santana, Luciana R B Gonçalves

Open access · hybridAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 16 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adriano H OliveiraDepartamento de Engenharia Química, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Cristiane C OgrodowskiFaculdade de Engenharia Química, Universidade Estadual de Campinas, Campinas, SP, Brazil.
André C de MacedoDepartamento de Engenharia Química, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Maria Helena A SantanaFaculdade de Engenharia Química, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Luciana R B GonçalvesDepartamento de Engenharia Química, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Universidade Federal do Ceará · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, natural cashew apple juice was used as cultivation medium as an alternative to substitute brain heart infusion medium. The effect of aeration and juice supplementation with yeast extract on the production of hyaluronic acid in batch fermentation was also investigated. Similar levels of cell mass were obtained in inoculum using cashew apple juice supplemented with yeast extract or the conventional brain heart infusion medium. Fermentation in Erlenmeyer flasks produced low biomass and hyaluronic acid concentrations. The hyaluronic acid concentration and viscosity increased from 0.15 g/L and 3.87 cP (no aeration or medium supplementation) to 1.76 g/L and 107 cP, when aeration (2 vvm) and 60 g/L of yeast extract were used. The results suggest the production of low-molecular weight hyaluronic acid oligomers instead of the high molecular weight polymer.

Indexed as

AnacardiumBiomassCulture MediaFermentationHyaluronic AcidSaccharomyces cerevisiaeCulture MediaHyaluronic Acidcashew apple juicehyaluronic acidsubmerged fermentation

Identifiers

PMID24688498
PMCPMC3958174
OpenAlexW2170108045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.