ArticleInternational journal of medical sciences2014
Discrepancy between serological and virological analysis of viral hepatitis in hemodialysis patients.
Article in International journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- The prevalence of hepatitis C virus in hemodialysis patients in Pakistan: A systematic review and meta-analysis.PloS one · 2020Pooled it
- Factors Correlating to the Development of Hepatitis C Virus Infection in Hemodialysis Patients-Findings Mainly from Asiatic Populations: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2019Pooled it
- Finding the Context of High-Risk Behavioral Factors and the Effectiveness of Addiction Treatment Centers in Preventing the Transmission of Hepatitis C Virus Among Injecting Drug Addicts: "Southeastern Iran".Health science reports · 2025Article
- Comedications and potential drug-drug interactions with direct-acting antivirals in hepatitis C patients on hemodialysis.Clinical and molecular hepatology · 2021Article
- The applicability of non-invasive methods for assessing liver fibrosis in hemodialysis patients with chronic hepatitis C.PloS one · 2020Article
- Do we really need more evidence to use hepatitis C positive donor kidney more liberally?Clinical kidney journal · 2017Article
- Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil.International journal of environmental research and public health · 2017Article
- Features of hepatitis C virus infection, current therapies and ongoing clinical trials in ten Asian Pacific countries.Hepatology international · 2015Review
- Huge gap between clinical efficacy and community effectiveness in the treatment of chronic hepatitis C: a nationwide survey in Taiwan.Medicine · 2015Article
- Laboratory Evaluation of Hepatitis C Virus Infection in Patients Undergoing Hemodialysis from North East India.Journal of clinical and experimental hepatologyArticle
- Seroprevalence of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among hemodialysis patients in a Tertiary Care Teaching Hospital in a developing country.Indian journal of sexually transmitted diseases and AIDSArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimViral hepatitis is a health threat for hemodialysis (HD) patients and it may be transmitted during treatment. Some patients categorized to have viral hepatitis were found to be non-viremic. To clarify the discrepancy between the serological tests in HD patients, we conducted the study.
methodsA total of 1681 HD patients was included. Blood samples were analyzed for hepatitis B surface antigen (HBsAg) and anti-hepatitis C antibody (anti-HCV). Detection of hepatitis B virus (HBV) DNA and hepatitis C virus (HCV) RNA were performed in either HBsAg (+) or anti-HCV (+) samples. HBV DNA/HCV RNA was also measured in a subset of HBsAg (-) and anti-HCV (-) patients. Liver function tests were analyzed and compared with the serological and virological tests.
resultsThe serological tests showed that 230 patients (13.7%) were HBsAg (+) and 290 (17.3%) were anti-HCV (+). We were unable to detect HBV DNA in 97 of 230 (42.2%) HBsAg (+) patients, and HCV RNA could not be found in 76 of 290 (26.2%) anti-HCV (+) patients. In 167 HBsAg (-) patients, only one showed a trace amount of HBV DNA. None of 151 anti-HCV (-) patients showed detectable HCV RNA. The prevalence rate of viral hepatitis remains high in Taiwanese HD patients: 13.7% for HBV and 17.3% for HCV. However, virological analysis showed 42.2% non-viremic rate for HBsAg and 26.2% non-viremic rate for anti-HCV.
conclusionsThe findings might challenge the presently suggested principles of bed and machine dedication and the diagnosis of viral hepatitis in HD patients.
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