ArticleGenetics and molecular biology2014
Obesity-related gene ADRB2, ADRB3 and GHRL polymorphisms and the response to a weight loss diet intervention in adult women.
Article in Genetics and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Article
- Development of a genetic risk score for obesity predisposition evaluation.Molecular genetics and genomics : MGG · 2022Article
- Stress does not induce a general transcription of transposable elements in Drosophila.Molecular biology reports · 2022Review
- Role of Leu72Met ofNutrients · 2022Article
- Genetic test for the prescription of diets in support of physical activity.Acta bio-medica : Atenei Parmensis · 2020Article
- Is it possible ABC transporters genetic variants influence the outcomes of a weight-loss diet in obese women?Genetics and molecular biology · 2020Article
- FTO rs9939609 A allele influences anthropometric outcome in response to dietary intervention, but not in response to physical exercise program.European journal of nutrition · 2019Article
- Heterozygosity for the rs696217 SNP in the Preproghrelin Gene Predicts Weight Loss After Bariatric Surgery in Severely Obese Individuals.Obesity surgery · 2017Article
- UCP2 expression is associated with weight loss after hypocaloric diet intervention.European journal of clinical nutrition · 2017Article
- Preliminary evidence for a role of the adrenergic nervous system in generalized anxiety disorder.Scientific reports · 2017Article
- Effects of energetic restriction diet on butyrylcholinesterase in obese women from southern Brazil - A longitudinal study.Archives of endocrinology and metabolismArticle
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Authors and funding
8 authors.
Funding
Abstract
The individual response to diet may be influenced by gene polymorphisms. This study hypothesized that ADRB2 (Gln27Glu, rs1042714 and Arg16Gly, rs1042713), ADRB3 (Trp64Arg, rs4994) and GHRL (Leu72Met, rs696217) polymorphisms moderate weight loss. The study was a seven weeks dietary weight loss intervention with Brazilian adult obese women (n = 109). The body mass index (BMI) was calculated and polymorphisms in these genes were assessed by real-time PCR assays. Two-way repeated-measures ANOVA (2 × 2) were used to analyze the intervention effect between polymorphisms and BMI over the period and after stratification for age and socioeconomic status (SES). The weight loss intervention resulted in decreased BMI over the seven-week period (p < 0.001), for high and low SES (p < 0.05) and mainly for participants with 30-49 y. The intervention did not result in a statistically significant difference in weight loss between polymorphism carriers and non-carriers, and although, the ADRB2, ADRB3 and GHRL polymorphisms did not moderate weight loss, the Gln27Glu polymorphism carriers showed a lower BMI compared to non-carriers in the low SES (p = 0.018) and the 30-39 y (p = 0.036) groups, suggesting a role for this polymorphism related to BMI control.
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