Evidence map›Paper›PMID 24687451›Full record

ReviewElectrophoresis2014

Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics.

Chenxi Yang, Xuefei Zhong, Lingjun Li

Abstract readReview
In one paragraph

Review in Electrophoresis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Proteomics of the heart.Physiological reviews · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chenxi YangDepartment of Chemistry, University of Wisconsin, Madison, WI, USA.
Xuefei Zhong
Lingjun Li

Funding

Proteomic Evaluation of the Blood-Brain Barrier Receptor-Mediated TransportomeR01NS071513 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SHUSTA, ERIC V · 2010 to 2013
$1.1M
Urinary Biomarkers of Lower Urinary Traxct Symptoms (LUTS) in Men P20DK097826 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI BUSHMAN, WADE A · 2012 to 2014
$776k
NIDDK NIH HHS P20 DK097826NINDS NIH HHS R01 NS071513
6 · The paper itself

Abstract

Due to the significance of protein phosphorylation in various biological processes and signaling events, new analytical techniques for enhanced phosphoproteomics have been rapidly introduced in the recent years. The combinatorial use of the phospho-specific enrichment techniques and prefractionation methods prior to MS analysis enable comprehensive profiling of the phosphoproteome and facilitate deciphering the critical roles that phosphorylation plays in signaling pathways in various biological systems. This review places special emphasis on the recent five-year (2009-2013) advances for enrichment and separation techniques that have been utilized for phosphopeptides prior to MS analysis.

Indexed as

AnimalsHumansMass SpectrometryPhosphopeptidesPhosphoproteinsProteomicsPhosphopeptidesPhosphoproteinsEnrichmentMass spectrometryPhosphopeptidesPhosphoproteomics/Separation

Identifiers

PMID24687451
PMCPMC4849134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.