Evidence map›Paper›PMID 24686884›Full record

Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2014

Communicating risk using absolute risk reduction or prolongation of life formats: cluster-randomised trial in general practice.

Charlotte Gry Harmsen, Ivar Sønbø Kristiansen, Pia Veldt Larsen, Jørgen Nexøe, Henrik Støvring, Dorte Gyrd-Hansen, Jesper Bo Nielsen, Adrian Edwards, Dorte Ejg Jarbøl

Open access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Pooled it
  4. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017
    Pooled it
  5. Risk scoring for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Communicating risk.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  14. Assessing, communicating, and managing risk in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Charlotte Gry HarmsenHead of Institute, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Ivar Sønbø Kristiansen
Pia Veldt Larsen
Jørgen Nexøe
Henrik Støvring
Dorte Gyrd-Hansen
Jesper Bo Nielsen
Adrian Edwards
Dorte Ejg Jarbøl
University of Oslo · NOUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is important that patients are well-informed about risks and benefits of therapies to help them decide whether to accept medical therapy. Different numerical formats can be used in risk communication but It remains unclear how the different formats affect decisions made by real-life patients.

aimTo compare the impact of using Prolongation Of Life (POL) and Absolute Risk Reduction (ARR) information formats to express effectiveness of cholesterol-lowering therapy on patients' redemptions of statin prescriptions, and on patients' confidence in their decision and satisfaction with the risk communication. DESIGN AND

settingCluster-randomised clinical trial in general practices. Thirty-four Danish GPs from 23 practices participated in a primary care-based clinical trial concerning use of quantitative effectiveness formats for risk communication in health prevention consultations.

methodGPs were cluster-randomised (treating practices as clusters) to inform patients about cardiovascular mortality risk and the effectiveness of statin treatment using either POL or ARR formats. Patients' redemptions of statin prescriptions were obtained from a regional prescription database. The COMRADE questionnaire was used to measure patients' confidence in their decision and satisfaction with the risk communication.

resultsOf the 240 patients included for analyses, 112 were allocated to POL information and 128 to ARR. Patients redeeming a statin prescription totalled six (5.4%) when informed using POL, and 32 (25.0%) when using ARR. The level of confidence in decision and satisfaction with risk communication did not differ between the risk formats.

conclusionPatients redeemed statin prescriptions less often when their GP communicated treatment effectiveness using POL compared with ARR.

Indexed as

Life Support CareNumbers Needed To TreatAdultAgedCardiovascular DiseasesCluster AnalysisDenmarkFemaleGeneral PracticeHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaMaleMiddle AgedProspective StudiesRisk AssessmentHydroxymethylglutaryl-CoA Reductase Inhibitorscardiovascular diseasedecision makinggeneral practicepatient participationrisk assessmentrisk communication

Identifiers

PMID24686884
PMCPMC3964454
OpenAlexW2070569359

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.