ReviewCurrent opinion in allergy and clinical immunology2014
Definition, etiology, and diagnosis of food protein-induced enterocolitis syndrome.
Review in Current opinion in allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025Review
- Article
- Non-IgE mediated food allergies in breastfed children: A clinical challenge.Allergologie select · 2022Review
- Review
- Clinical significance of positive fecal occult blood test in neonates.Scientific reports · 2019Article
- Metabolic acidosis as Food Protein Induced Enterocolitis Syndrome (FPIES) onset in a newborn.Italian journal of pediatrics · 2018Article
- Food Protein-Induced Enterocolitis Syndrome (FPIES): Review of Recent Guidelines.Current allergy and asthma reports · 2018Review
- Aggressive gastrointestinal food allergy in neonates and its possible relationship to necrotizing enterocolitis.International journal of surgery case reports · 2017Article
- FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome.Case reports in pediatrics · 2016Article
- High Prevalence of Neutrophil Cytoplasmic Autoantibodies in Infants with Food Protein-Induced Proctitis/Proctocolitis: Autoimmunity Involvement?Journal of immunology research · 2015Article
- The development of a standardised diet history tool to support the diagnosis of food allergy.Clinical and translational allergy · 2015Article
- Unmet needs in food protein-induced enterocolitis syndrome.Current opinion in allergy and clinical immunology · 2014Article
- Differential diagnosis of food protein-induced enterocolitis syndrome.Current opinion in allergy and clinical immunology · 2014Review
- Food protein-induced enterocolitis syndrome and allergic proctocolitis.Allergy and asthma proceedingsReview
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewFood protein-induced enterocolitis syndrome (FPIES) is a poorly understood non-IgE-mediated food hypersensitivity, primarily affecting infants and toddlers. There are few data regarding pathophysiology of FPIES that suggest local intestinal imbalance between TNF-α and TGF-β. Patients frequently present with multiple reactions, which are characterized by projectile, repetitive emesis, dehydration, lethargy, and failure to thrive. Despite the severity of presentation, the diagnosis is frequently delayed, and patients often undergo extensive and invasive evaluation prior to reaching the diagnosis. RECENT
findingsReviews published in the last year provide a general approach to diagnosis and management of FPIES and aim to increase awareness and understanding of FPIES among general pediatricians. SUMMARY: Multicenter studies are necessary to reevaluate and modify the oral food challenge criteria. Research on the pathophysiology of FPIES reactions is necessary to provide insight into the evidence-based approach to diagnosis and management of FPIES. Registries are needed to understand the phenotype, triggers, and prevalence of FPIES.
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