Evidence map›Paper›PMID 24685563›Full record

ArticleDrug and alcohol dependence2014

Time to relapse following treatment for methamphetamine use: a long-term perspective on patterns and predictors.

Mary-Lynn Brecht, Diane Herbeck

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary-Lynn BrechtIntegrated Substance Abuse Programs, Department of Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, 11075 Santa Monica Blvd., Suite 100, Los Angeles, CA 90025, United States; School of Nursing, University of California, Los Angeles, Factor 5-151, 700 Tiverton Ave., Los Angeles, CA 90095, United States. Electronic address: lbrecht@ucla.edu.
Diane HerbeckIntegrated Substance Abuse Programs, Department of Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, 11075 Santa Monica Blvd., Suite 100, Los Angeles, CA 90025, United States.

Funding

STATISTICAL SUPPORT/DATA MANAGEMENT COREP30DA016383 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING · 2005 to 2015
$8.6M
Methamphetamine Abuse: Long-Term Trajectories, Correlates, Treatment EffectsR01DA025113 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRECHT, MARY-LYNN · 2009 to 2012
$2.3M
METHAMPHETAMINE ABUSE--NATURAL HISTORY,TREATMENT EFFECTSR01DA011020 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRECHT, MARY-LYNN · 1998 to 2003
$1.9M
NIDA NIH HHS P30 DA016383NIDA NIH HHS P30DA016383-06NIDA NIH HHS R01 DA011020NIDA NIH HHS R01 DA025113NIDA NIH HHS R01DA025113NIDA NIH HHS R01DA11020
6 · The paper itself

Abstract

introductionThis paper describes methamphetamine (MA) use patterns, specifically the duration of continuing abstinence ("time to relapse") for periods averaging 5 years post-discharge from treatment for MA use, and the relationship with selected user and treatment characteristics.

methodsA sample of 350 treatment admissions from a large county substance use disorder (SUD) treatment system was randomly selected (within gender, race/ethnicity, treatment modality strata). Retrospective self-report data are from natural history interviews (NHI) conducted approximately 3 years after treatment and a follow-up of 2-3 years later. Relapse is defined as any use of MA with time as the number of months of continuous MA abstinence after treatment discharge until relapse. This outcome was constructed from a monthly MA use timeline using NHI data. A Cox model was used to examine time to relapse and predictors.

resultsSixty-one percent of the sample relapsed to MA use within 1 year after treatment discharge and 14% during years 2-5. Significant protective factors predicting longer time to relapse included having experienced serious MA-related psychiatric/behavioral problems (hazard ratio [HR]=0.75, p=0.027), longer duration of the index treatment episode (HR=0.93, p=0.001), and participating in self-help or other treatment during the post-treatment abstinence period (HR=0.29, p<0.001); risk factors for shorter time to relapse included having a parent with alcohol and/or drug use problems (HR=1.35, p=0.020) and involvement in MA sales (HR=1.48, p=0.002).

conclusionsResults contribute a long-term perspective on patterns of MA use following treatment and support a need for early post-treatment and long-term continuing care and relapse-prevention services.

Indexed as

MethamphetamineAdultAmphetamine-Related DisordersChild of Impaired ParentsFemaleHumansInterviews as TopicLos AngelesMaleProportional Hazards ModelsRecurrenceRetrospective StudiesRisk FactorsTime FactorsMethamphetamineContinuing abstinenceCox regressionLong-term follow-upMethamphetamineNatural history interviewRelapse

Identifiers

PMID24685563
PMCPMC4550209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.