ReviewFrontiers in neuroendocrinology2014
Rapid effects of estrogens on behavior: environmental modulation and molecular mechanisms.
Review in Frontiers in neuroendocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes.Environmental health perspectives · 2015Pooled it
- The effects of estradiol on mood and behavior in human female adolescents: a systematic review.European journal of pediatrics · 2015Pooled it
- Gut microbiome community structure correlates with different behavioral phenotypes in the Belyaev Farm-Fox Experiment.Communications biology · 2026Article
- Brain Nuclei in the Regulation of Sexual Behavior, Peripheral Nerves Related to Reproduction, and Their Alterations in Neurodegenerative Diseases: A Brief Review.Brain sciences · 2025Review
- Estrogen Control of Social Behaviors.Annual review of neuroscience · 2025Review
- Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice.Nature communications · 2024Article
- Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders.BMC neuroscience · 2023Review
- Genomic analysis of Tibetan ground tits identifies molecular adaptations associated with cooperative breeding.Current zoology · 2023Article
- Social memory in female mice is rapidly modulated by 17β-estradiol through ERK and Akt modulation of synapse formation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Anatomical and molecular features of the amygdalohippocampal transition area and its role in social and emotional behavior processes.Neuroscience and biobehavioral reviews · 2022Review
- The steroid hormone estriol (EBMC biology · 2022Article
- Mental Resilience and Coping With Stress: A Comprehensive, Multi-level Model of Cognitive Processing, Decision Making, and Behavior.Frontiers in behavioral neuroscience · 2021Article
- A Sensitive Impedimetric Aptasensor Based on Carbon Nanodots Modified Electrode for Detection of 17ß-Estradiol.Nanomaterials (Basel, Switzerland) · 2020Article
- Oligodendrocytes Death Induced Sensorimotor and Cognitive Deficit in N-nitro-L-arginine methyl Rat Model of Pre-eclampsia.Neurochemical research · 2020Article
- The dark ventral patch: A bimodal flexible trait related to male competition in red deer.PloS one · 2020Article
- Melatonin mediates seasonal transitions in aggressive behavior and circulating androgen profiles in male Siberian hamsters.Hormones and behavior · 2020Article
- Personality and gonadal development as sources of individual variation in response to GnRH challenge in female great tits.Proceedings. Biological sciences · 2019Article
- Structural plasticity of the hippocampus in response to estrogens in female rodents.Molecular brain · 2019Review
- Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice.Endocrinology · 2018Article
- Rapid effects of 17β-estradiol on aggressive behavior in songbirds: Environmental and genetic influences.Hormones and behavior · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Estradiol can modulate neural activity and behavior via both genomic and nongenomic mechanisms. Environmental cues have a major impact on the relative importance of these signaling pathways with significant consequences for behavior. First we consider how photoperiod modulates nongenomic estrogen signaling on behavior. Intriguingly, short days permit rapid effects of estrogens on aggression in both rodents and song sparrows. This highlights the importance of considering photoperiod as a variable in laboratory research. Next we review evidence for rapid effects of estradiol on ecologically-relevant behaviors including aggression, copulation, communication, and learning. We also address the impact of endocrine disruptors on estrogen signaling, such as those found in corncob bedding used in rodent research. Finally, we examine the biochemical mechanisms that may mediate rapid estrogen action on behavior in males and females. A common theme across these topics is that the effects of estrogens on social behaviors vary across different environmental conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.