Evidence map›Paper›PMID 24685313›Full record

ReviewEuropean journal of internal medicine2014

Management of nontuberculous mycobacterial infection in the elderly.

Mehdi Mirsaeidi, Maham Farshidpour, Golnaz Ebrahimi, Stefano Aliberti, Joseph O Falkinham

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in European journal of internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01680822 (Treatment Outcomes in Patient With Nontuberculous Mycobacterial Disease in the University of Illinois Hospital & Health Sciences System), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01680822 terminatednot on this map

Treatment Outcomes in Patient With Nontuberculous Mycobacterial Disease in the University of Illinois Hospital & Health Sciences System

TypeobservationalSponsorUniversity of Illinois at ChicagoRan2012 to 2014Enrolled150ConditionsNontuberculous Mycobacterial Disease, Atypical Mycobacterium Infections
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Case report: co-infection ofAME case reports · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Variability in the Management of Adults With Pulmonary Nontuberculous Mycobacterial Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mehdi MirsaeidiSection of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine M/C 719, University of IL at Chicago, USA. Electronic address: mmirsae@uic.edu.
Maham FarshidpourInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Golnaz EbrahimiSection of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine M/C 719, University of IL at Chicago, USA.
Stefano AlibertiDepartment of Health Science, University of Milan Bicocca, Clinica Pneumologica, AO San Gerardo, Via Pergolesi 33, Monza, Italy.
Joseph O FalkinhamDepartment of Biological Science, University of Virginia Tech, Blacksburg, VA, USA.
University of Illinois Chicago · USUniversity of Maryland, Baltimore · USUniversity of Milano-Bicocca · ITUniversity of Virginia · US

Funding

Pulmonary and Critical Care Post-Doctoral Research Training ProgramT32HL082547 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FINN, PATRICIA W · 2007 to 2017
$2.7M
NHLBI NIH HHS T32 HL082547
6 · The paper itself

Abstract

The incidence of nontuberculous mycobacteria (NTM) has increased over the last decades. Elderly people are more susceptible to NTM and experience increased morbidities. NTM incidence is expected to rise due to an increasing elderly population at least up to 2050. Given the importance of NTM infection in the elderly, an increasing interest exists in studying NTM characteristics in the aged population. In this review, we summarize the characteristics of NTM infection among elderly patients. We focus on epidemiology, clinical presentation, and treatment options of NTM in this age group. We highlight the differences in the diagnosis and treatment between rapid and slow growing mycobacterial infections. The current recommendation for treatment of NTM is discussed. We debate if in vitro susceptibility testing has a role in the treatment of NTM. Drug-drug interaction between antibiotics used to treat NTM and other medications, particularly warfarin, is another important issue that we discuss. Finally, we review the prognosis of NTM disease in elderly patients.

Indexed as

Nontuberculous MycobacteriaAgedAge FactorsAnti-Bacterial AgentsHumansMycobacterium Infections, NontuberculousPrevalencePrognosisAnti-Bacterial AgentsElderlyNontuberculous mycobacteriumNTMTreatment

Identifiers

PMID24685313
PMCPMC4067452
OpenAlexW2017990323

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.