SynthesisBMC ophthalmology2014
Trabeculectomy with versus without releasable sutures for glaucoma: a meta-analysis of randomized controlled trials.
Synthesis in BMC ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Pooled it
- Choroidal thickness and high myopia: a cross-sectional study and meta-analysis.BMC ophthalmology · 2015Pooled it
- Association of TCF4 polymorphisms and Fuchs' endothelial dystrophy: a meta-analysis.BMC ophthalmology · 2015Pooled it
- Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol.The British journal of ophthalmology · 2018Trial
- Trends in Glaucoma Fellowship Surgical Experience.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Factors Correlated With Mid-Term Morphology of Functional Blebs Following Implantation of Preserflo MicroShunt Using AS-OCT.Translational vision science & technology · 2023Article
- Results of modified COLasers in medical science · 2022Article
- Secondary epiretinal membrane after Ex-Press glaucoma filtration device implant.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- [Treatment success of canaloplasty and trabeculectomy by the same surgeon with the same level of experience in the long-term course].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Article
- Stab incision mitomycin C-assisted rapid trabeculectomy: A 'SMART' trabeculectomy alternative.Experimental and therapeutic medicine · 2020Article
- The prognosis of trabeculectomy in primary angle-closure glaucoma patients.International journal of ophthalmology · 2019Article
- Choroidal thickness in pregnant women: a cross-sectional study.International journal of ophthalmology · 2016Article
- Trabeculectomy: is releasable suture trabeculectomy a cause of better bleb?Romanian journal of ophthalmologyArticle
- Evaluating glaucoma surgeries in the MIGS context.Romanian journal of ophthalmologyReview
- Revisiting Results of Conventional Surgery: Trabeculectomy, Glaucoma Drainage Devices, and Deep Sclerectomy in the Era of MIGS.Journal of current glaucoma practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to compare the efficacy and tolerability of trabeculectomies performed with and without releasable sutures in the treatment of patients with uncontrolled glaucoma.
methodsA comprehensive literature meta-analysis was performed, comparing trabeculectomies performed with and without releasable sutures. The primary efficacy measure was the weighted mean difference (WMD) in percentage intraocular pressure reduction (IOPR%) at the follow-up end point. The secondary efficacy measure was the risk ratio (RR) for complete and qualified success rates of trabeculectomy at the follow-up end point. Trabeculectomy tolerability estimates were measured by the RR for adverse events. All the outcomes were reported with a 95% confidence interval (CI).
resultsThe WMD of the IOPR% from baseline was -4.56 (range -9.24-0.12) when trabeculectomies without releasable sutures were compared with trabeculectomies with releasable sutures. Trabeculectomies with releasable sutures were associated with numerically greater, but nonsignificant, efficacy in terms of lowered IOP compared with trabeculectomies without releasable sutures. The complete and qualified success rate of the two surgical procedures were comparable, with RRs of 0.92 (range 0.80-1.04) and 0.99 (range 0.89-1.11), respectively, at the follow-up endpoints. Trabeculectomies without releasable sutures were associated with a significantly higher frequency of hypotony and flat anterior chambers than trabeculectomies with releasable sutures, with pooled RRs of 4.04 (range 1.88-8.68) and 2.57 (range 1.25-5.30), respectively.
conclusionAlthough the two surgical procedures resulted in equivalent efficacy in IOP control, the trabeculectomies performed with releasable sutures were better tolerated than those without releasable sutures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.