ArticleWorld journal of surgical oncology2014
Drug dosage in isolated limb perfusion: evaluation of a limb volume model for extremity volume calculation.
Article in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Oral contraceptives and menstrual cycle influence autonomic reflex function.Physiological reports · 2020Trial
- Optimizing isolated limb perfusion in malignant melanoma and sarcoma: Key factors influencing postoperative outcomes and complications.Medicine · 2026Article
- A Percutaneous, High-Flow, Hyperthermic Isolated Limb Perfusion Technique for Extremity Malignancies: Point of Technique.Journal of surgical oncology · 2026Article
- The effect of prolonged complex decongestive therapy for lower limb secondary lymphedema.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- [Hyperthermic isolated limb perfusion with TNF-alpha and melphalan for the treatment of locally advanced soft-tissue sarcoma].Operative Orthopadie und Traumatologie · 2026Article
- Lower extremity lymphedema in patients with gynecologic cancer: Validation of the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) in German language and investigation of lymphedema real-world treatment.Archives of gynecology and obstetrics · 2025Observational
- Isolated Limb Perfusion for Extremity Soft Tissue Sarcoma and Malignant Melanoma.Indian journal of surgical oncology · 2024Review
- The influence of oral contraceptives on the exercise pressor reflex in the upper and lower body.Physiological reports · 2024Article
- Isolated Limb Perfusion of Upper Limb: How I Do It.Indian journal of surgical oncology · 2022Article
- Soft Tissue Cancer Management: Isolated Limb Infusion for Sarcoma.Visceral medicine · 2019Article
- [Isolated limb perfusion for liposarcoma : Histopathological response and subgroup analysis after TNF melphalan-based ILP].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017Article
- Regional therapies for in-transit disease.Surgical oncology clinics of North America · 2015Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExact drug dosing in isolated limb perfusion (ILP) and infusion (ILI) is essential. We developed and evaluated a model for calculating the volume of extremities and compared this model with body weight- and height-dependent parameters.
methodsThe extremity was modeled by a row of coupled truncated cones. The sizes of the truncated cone bases were derived from the circumference measurements of the extremity at predefined levels (5 cm). The resulting volumes were added. This extremity volume model was correlated to the computed tomography (CT) volume data of the extremity (total limb volume). The extremity volume was also correlated with the patient's body weight, body mass index (BMI) and ideal body weight (IBW). The no-fat CT limb volume was correlated with the circumference-measured limb volume corrected by the ideal-body-weight to actual-body-weight ratio (IBW corrected-limb-volume).
resultsThe correlation between the CT volume and the volume measured by the circumference was high and significant. There was no correlation between the limb volume and the bare body weight, BMI or IBW. The correlation between the no-fat CT volume and IBW-corrected limb volume was high and significant.
conclusionsAn appropriate drug dosing in ILP can be achieved by combining the limb volume with the simple circumference measurements and the IBW to body-weight ratio.
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