ArticleVirology journal2014
Epidemiological and molecular features of dengue virus type-1 in New Caledonia, South Pacific, 2001-2013.
Article in Virology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 48 citations in OpenAlex.
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- Adaptive Evolution as a Driving Force of the Emergence and Re-Emergence of Mosquito-Borne Viral Diseases.Viruses · 2022Review
- Arboviral Disease Outbreaks in the Pacific Islands Countries and Areas, 2014 to 2020: A Systematic Literature and Document Review.Pathogens (Basel, Switzerland) · 2022Review
- Potential role of vector-mediated natural selection in dengue virus genotype/lineage replacements in two epidemiologically contrasted settings.Emerging microbes & infections · 2021Article
- Using Background Sequencing Data to Anticipate DENV-1 Circulation in the Lao PDR.Microorganisms · 2021Article
- Assessment of fitness and vector competence of a New Caledonia wMel Aedes aegypti strain before field-release.PLoS neglected tropical diseases · 2021Article
- Development of a bedside score to predict dengue severity.BMC infectious diseases · 2021Article
- The Absence of Yellow Fever in Asia: History, Hypotheses, Vector Dispersal, Possibility of YF in Asia, and Other Enigmas.Viruses · 2020Review
- Molecular Characterization of Dengue Type 2 Outbreak in Pacific Islands Countries and Territories, 2017-2020.Viruses · 2020Article
- Trends of the Dengue Serotype-4 Circulation with Epidemiological, Phylogenetic, and Entomological Insights in Lao PDR between 2015 and 2019.Pathogens (Basel, Switzerland) · 2020Article
- Assessing entomological risk factors for arboviral disease transmission in the French Territory of the Wallis and Futuna Islands.PLoS neglected tropical diseases · 2020Article
- Vector competence of Aedes aegypti from New Caledonia for the four recent circulating dengue virus serotypes.PLoS neglected tropical diseases · 2020Article
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- Multiple arboviral infections during a DENV-2 outbreak in Solomon Islands.Tropical medicine and health · 2020Article
- Spatio-temporal distribution analysis of circulating genotypes of dengue virus type 1 in western and southern states of India by a one-step real-time RT-PCR assay.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019Article
- Evolution of Subgenomic RNA Shapes Dengue Virus Adaptation and Epidemiological Fitness.iScience · 2019Article
- Dengue in New Caledonia: Knowledge and Gaps.Tropical medicine and infectious disease · 2019Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
Abstract
backgroundThe epidemiology of dengue in the South Pacific has been characterized by transmission of a single dominant serotype for 3-5 years, with subsequent replacement by another serotype. From 2001 to 2008 only DENV-1 was reported in the Pacific. In 2008, DENV-4 emerged and quickly displaced DENV-1 in the Pacific, except in New Caledonia (NC) where DENV-1 and DENV-4 co-circulated in 2008-2009. During 2012-2013, another DENV-1 outbreak occurred in NC, the third DENV-1 outbreak in a decade. Given that dengue is a serotype-specific immunizing infection, the recurrent outbreaks of a single serotype within a 10-year period was unexpected.
findingsThis study aimed to inform this phenomenon by examining the phylogenetic characteristics of the DENV-1 viruses in NC and other Pacific islands between 2001 and 2013. As a result, we have demonstrated that NC experienced introductions of viruses from both the Pacific (genotype IV) and South-east Asia (genotype I). Moreover, whereas genotype IV and I were co-circulating at the beginning of 2012, we observed that from the second half of 2012, i.e. during the major DENV-1 outbreak, all analyzed viruses were genotype I suggesting that a genotype switch occurred.
conclusionsRepeated outbreaks of the same dengue serotype, as observed in NC, is uncommon in the Pacific islands. Why the earlier DENV-1 outbreaks did not induce sufficient herd immunity is unclear, and likely multifactorial, but the robust vector control program may have played a role by limiting transmission and thus maintaining a large susceptible pool in the population.
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