Evidence map›Paper›PMID 24683425›Full record

ArticleJournal of military and veterans' health2013

Method Issues in Epidemiological Studies of Medically Unexplained Symptom-based Conditions in Veterans.

Steven S Coughlin, Rebecca B McNeil, Dawn T Provenzale, Erin K Dursa, Catherine M Thomas

Open access · greenAbstract read
In one paragraph

Article in Journal of military and veterans' health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Gulf War Women's Health Cohort: Study Design and Protocol.International journal of environmental research and public health · 2020
    Article
  5. Review
  6. Gastrointestinal neuroimmune disruption in a mouse model of Gulf War illness.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  7. Rates of Chronic Medical Conditions in 1991 Gulf War Veterans Compared to the General Population.International journal of environmental research and public health · 2019
    Article
  8. A Neuroimmune Model of Gulf War Illness.Journal of environment and health sciences · 2017
    Article
  9. A Review of Epidemiologic Studies of the Health of Gulf War Women Veterans.Journal of environment and health sciences · 2017
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Steven S CoughlinDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Rebecca B McNeilDurham Epidemiologic Research and Information Center, Veterans Affairs Medical Center, Durham, NC.
Dawn T ProvenzaleDurham Epidemiologic Research and Information Center, Veterans Affairs Medical Center, Durham, NC ; Division of Gastroenterology, Duke University Medical Center, Durham, NC.
Erin K DursaEpidemiology Program, Post-deployment Health Group, Office of Public Health, Department of Veterans Affairs, Washington, DC.
Catherine M ThomasDurham Epidemiologic Research and Information Center, Veterans Affairs Medical Center, Durham, NC.
Emory University · US

Funding

EPIDEMIOLOGY OF IDIOPATHIC DILATED CARDIOMYOPATHYR29HL044904 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI COUGHLIN, STEVEN S · 1990 to 1994
–
NHLBI NIH HHS R29 HL044904
6 · The paper itself

Abstract

Symptom-based conditions such as chronic fatigue syndrome (CFS) and medically unexplained multi-symptom illness (MSI) are fairly common in the general population and are also important veteran's health concerns due to their higher frequency among U.S. veterans who served during the 1990-1991 Gulf War. CFS, MSI, and other symptom-based conditions are often associated with considerable morbidity due to fatigue, chronic pain, neurologic symptoms, and other symptoms that can impair the quality of life. This article discusses several important issues of methodology that arise in population studies of CFS and MSI. These include the exclusion criteria that have been used in population studies to define CFS-like illness and unexplained MSI, the potential for false positive and false negative assessments of illness status, the potential for sex differences, and the poorly understood natural history of these symptom-based conditions across the life span. As an empirical example of these methodology issues, we examined existing data from a 2005 follow-up survey. We found that 64.9% (762 of 1,175) of female Gulf War veterans and 53.4% (2,530 of 4,739) of male Gulf War veterans had 1 or more exclusionary medical conditions. The prevalence among veterans with one or more exclusionary medical conditions increased markedly by age among females and those with a low income.

Indexed as

chronic fatigue syndromeepidemiologic methodsGulf Warmedically explained multi-symptom illnessmenopausesurveyveterans

Identifiers

PMID24683425
PMCPMC3968909
OpenAlexW1582601990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.