Evidence map›Paper›PMID 24683398›Full record

ArticlePostepy dermatologii i alergologii2014

Omalizumab as a new therapeutic approach for children with severe asthma.

Joanna Jerzyńska, Anna Sztafińska, Katarzyna Woicka-Kolejwa, Iwona Stelmach

Abstract readCase Reports
In one paragraph

Article in Postepy dermatologii i alergologii, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna JerzyńskaDepartment of Pediatrics and Allergy, Medical University of Lodz, Poland. Head of Department: Prof. Iwona Stelmach MD, PhD.
Anna SztafińskaDepartment of Pediatrics and Allergy, Medical University of Lodz, Poland. Head of Department: Prof. Iwona Stelmach MD, PhD.
Katarzyna Woicka-KolejwaDepartment of Pediatrics and Allergy, Medical University of Lodz, Poland. Head of Department: Prof. Iwona Stelmach MD, PhD.
Iwona StelmachDepartment of Pediatrics and Allergy, Medical University of Lodz, Poland. Head of Department: Prof. Iwona Stelmach MD, PhD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omalizumab has been shown to improve asthma control when added to a regimen of guideline-based therapy for inner-city children and adolescents, nearly eliminating seasonal peaks in exacerbation and reducing the need for other medications to control asthma. Below, we describe a case of a 17-year-old non-smoker with a history of severe asthma admitted to our clinic after unsuccessful 10-year immunotherapy. The patient fulfilled the criteria for anti-IgE therapy, he was prescribed omalizumab 600 mg every 2 weeks. During therapy he was able to reduce his use of ICS and did not require any oral corticosteroids. He experienced an increase in his ability to exercise and noted no exacerbation of asthma symptoms. It is possible that in our patient, specific immunotherapy could be successfully continued after the initiation of omalizumab therapy.

Indexed as

immunotherapyomalizumabsevere asthma

Identifiers

PMID24683398
PMCPMC3952056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.