Evidence map›Paper›PMID 24682990›Full record

ReviewJournal of microbiology (Seoul, Korea)2014

Nontraditional therapies to treat Helicobacter pylori infection.

Morris O Makobongo, Jeremy J Gilbreath, D Scott Merrell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Frontiers in microbiology · 2024
    Review
  2. Article
  3. Targeting the Essential Transcription Factor HP1043 ofFrontiers in molecular biosciences · 2022
    Article
  4. World journal of gastroenterology · 2021
    Review
  5. A Comprehensive Study on the Antimicrobial Properties of Resveratrol as an Alternative Therapy.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  6. Article
  7. Selective killing ofProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  8. Gut and liver · 2017
    Article
  9. Article
  10. Article
  11. Antibiotic treatment for Helicobacter pylori: Is the end coming?World journal of gastrointestinal pharmacology and therapeutics · 2015
    Review
  12. Dietary amelioration of Helicobacter infection.Nutrition research (New York, N.Y.) · 2015
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Morris O MakobongoDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.
Jeremy J Gilbreath
D Scott Merrell
Uniformed Services University of the Health Sciences · US

Funding

Regulatory Networks of Helicobacter pyloriR01AI065529 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI MERRELL, D. SCOTT · 2007 to 2011
$1.9M
NIAID NIH HHS R01AI065529
6 · The paper itself

Abstract

The Gram-negative pathogen Helicobacter pylori is increasingly more resistant to the three major antibiotics (metronidazole, clarithromycin and amoxicillin) that are most commonly used to treat infection. As a result, there is an increased rate of treatment failure; this translates into an overall higher cost of treatment due to the need for increased length of treatment and/or the requirement for combination or sequential therapy. Given the rise in antibiotic resistance, the complicated treatment regime, and issues related to patient compliance that stem from the duration and complexity of treatment, there is clearly a pressing need for the development of novel therapeutic strategies to combat H. pylori infection. As such, researchers are actively investigating the utility of antimicrobial peptides, small molecule inhibitors and naturopathic therapies. Herein we review and discuss each of these novel approaches as a means to target this important gastric pathogen.

Indexed as

Anti-Bacterial AgentsBiological ProductsDrug Resistance, BacterialHelicobacter InfectionsHelicobacter pyloriHumansAnti-Bacterial AgentsBiological Products

Identifiers

PMID24682990
OpenAlexW2066035552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.