ReviewCellular and molecular life sciences : CMLS2014
Tracking migration during human T cell development.
Review in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 38 citations in OpenAlex.
- Morphometric analysis of the thymic epithelial cell network using integrated and orthogonal digital pathology approaches.Communications biology · 2026Article
- A human NK cell progenitor that originates in the thymus and generates KIRScience advances · 2025Article
- EdU tracking of leukocyte recruitment in mouse models of ischemic stroke and sterile lung inflammation.Journal of cell science · 2025Article
- Intrathymic Cell Migration: Implications in Thymocyte Development and T Lymphocyte Repertoire Formation.Advances in experimental medicine and biology · 2025Review
- Article
- Unraveling the spatial organization and development of human thymocytes through integration of spatial transcriptomics and single-cell multi-omics profiling.Nature communications · 2024Article
- Comparative transcriptome analysis of T lymphocyte subpopulations and identification of critical regulators defining porcine thymocyte identity.Frontiers in immunology · 2024Article
- A spatial human thymus cell atlas mapped to a continuous tissue axis.bioRxiv : the preprint server for biology · 2023Article
- Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation.Bioengineering & translational medicine · 2023Article
- Studying T Cell Development in Neonatal and Adult Thymic Slices.Methods in molecular biology (Clifton, N.J.) · 2023Article
- T-Cell Progenitors As A New Immunotherapy to Bypass Hurdles of Allogeneic Hematopoietic Stem Cell Transplantation.Frontiers in immunology · 2022Review
- Broad genomic workup including optical genome mapping uncovers aFrontiers in oncology · 2022Article
- Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development.Frontiers in genetics · 2021Article
- Current and Future Therapeutic Approaches for Thymic Stromal Cell Defects.Frontiers in immunology · 2021Review
- Novel Combination of Surface Markers for the Reliable and Comprehensive Identification of Human Thymic Epithelial Cells by Flow Cytometry: Quantitation and Transcriptional Characterization of Thymic Stroma in a Pediatric Cohort.Frontiers in immunology · 2021Article
- Pleiotropic Roles of VEGF in the Microenvironment of the Developing Thymus.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- TheProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Tumor progression mechanisms: Insights from the central immune regulation of tissue homeostasis.Oncology letters · 2019Review
- Small interference ITGA6 gene targeting in the human thymic epithelium differentially regulates the expression of immunological synapse-related genes.Cell adhesion & migration · 2018Article
- Cultured Human Thymic-Derived Cells Display Medullary Thymic Epithelial Cell Phenotype and Functionality.Frontiers in immunology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Specialized microenvironments within the thymus are comprised of unique cell types with distinct roles in directing the development of a diverse, functional, and self-tolerant T cell repertoire. As they differentiate, thymocytes transit through a number of developmental intermediates that are associated with unique localization and migration patterns. For example, during one particular developmental transition, immature thymocytes more than double in speed as they become mature T cells that are among the fastest cells in the body. This transition is associated with dramatic changes in the expression of chemokine receptors and their antagonists, cell adhesion molecules, and cytoskeletal components to direct the maturing thymocyte population from the cortex to medulla. Here we discuss the dynamic changes in behavior that occur throughout thymocyte development, and provide an overview of the cell-intrinsic and extrinsic mechanisms that regulate human thymocyte migration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.