ReviewProtoplasma2014
Metal/metalloid stress tolerance in plants: role of ascorbate, its redox couple, and associated enzymes.
Review in Protoplasma, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 160 citations in OpenAlex.
- ChERF017, an ERF transcription factor, confers cadmium stress tolerance in Cerasus humilis.BMC plant biology · 2026Article
- Allelopathic Activity of Ginseng-Cultivated Soil: Extracts on Seed Germination and Growth of Five Vegetables in China.Plants (Basel, Switzerland) · 2026Article
- New progress in the production, oxidative damage, and scavenging mechanisms of reactive oxygen species in plants under abiotic stress.Frontiers in plant science · 2026Review
- Evolutionary analysis of ascorbate-glutathione cycle genes across green plants with lineage-specific profiling in grapevine (Horticulture research · 2026Article
- Integrated transcriptomics and metabolomics to explore the mechanisms of Elaeagnus mollis diels seed viability decline.BMC genomics · 2025Article
- Comparative physiological and transcriptomic analyses reveal genotype specific response to drought stress in Siberian wildrye (Elymus sibiricus).Scientific reports · 2024Article
- Effect of Oak Powdery Mildew on Ascorbate-Glutathione Cycle and Other Antioxidants in Plant-Cells · 2024Article
- Kiwifruit bZIP transcription factor AcePosF21 elicits ascorbic acid biosynthesis during cold stress.Plant physiology · 2023Article
- Effect of Thallium(I) on Growth, Nutrient Absorption, Photosynthetic Pigments, and Antioxidant Response ofAntioxidants (Basel, Switzerland) · 2023Article
- The Disturbance of the Antioxidant System Results in Internal Blue Discoloration of Postharvest Cherry Radish (Foods (Basel, Switzerland) · 2023Article
- Phytoremediation of Potentially Toxic Elements: Role, Status and Concerns.Plants (Basel, Switzerland) · 2023Review
- Foliar Application of Spermidine Alleviates Waterlogging-Induced Damages to Maize Seedlings by Enhancing Antioxidative Capacity, Modulating Polyamines and Ethylene Biosynthesis.Life (Basel, Switzerland) · 2022Article
- Postharvest treatments with MnClScientific reports · 2022Article
- Transcriptome Analyses in a Selected Gene Set Indicate Alternative Oxidase (AOX) and Early Enhanced Fermentation as Critical for Salinity Tolerance in Rice.Plants (Basel, Switzerland) · 2022Article
- Effect of Water Supplementation on Oxidant/Antioxidant Activities and Total Phenol Content in Growing Olives of the Morisca and Manzanilla Varieties.Antioxidants (Basel, Switzerland) · 2022Article
- How to Cope with the Challenges of Environmental Stresses in the Era of Global Climate Change: An Update on ROS Stave off in Plants.International journal of molecular sciences · 2022Review
- Heavy Metal Effects on Biodiversity and Stress Responses of Plants Inhabiting Contaminated Soil in Khulais, Saudi Arabia.Biology · 2022Article
- Characterization of physiological and antioxidant responses inFrontiers in plant science · 2022Article
- Early gene expression response of barley root tip to toxic concentrations of cadmium.Plant molecular biology · 2022Article
- Biochemical responses of hairgrass (Frontiers in plant science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The enhanced generation of reactive oxygen species (ROS) under metal/metalloid stress is most common in plants, and the elevated ROS must be successfully metabolized in order to maintain plant growth, development, and productivity. Ascorbate (AsA) is a highly abundant metabolite and a water-soluble antioxidant, which besides positively influencing various aspects in plants acts also as an enigmatic component of plant defense armory. As a significant component of the ascorbate-glutathione (AsA-GSH) pathway, it performs multiple vital functions in plants including growth and development by either directly or indirectly metabolizing ROS and its products. Enzymes such as monodehydroascorbate reductase (MDHAR, EC 1.6.5.4) and dehydroascorbate reductase (DHAR, EC 1.8.5.1) maintain the reduced form of AsA pool besides metabolically controlling the ratio of AsA with its oxidized form (dehydroascorbate, DHA). Ascorbate peroxidase (APX, EC 1.11.1.11) utilizes the reduced AsA pool as the specific electron donor during ROS metabolism. Thus, AsA, its redox couple (AsA/DHA), and related enzymes (MDHAR, DHAR, and APX) cumulatively form an AsA redox system to efficiently protect plants particularly against potential anomalies caused by ROS and its products. Here we present a critical assessment of the recent research reports available on metal/metalloid-accrued modulation of reduced AsA pool, AsA/DHA redox couple and AsA-related major enzymes, and the cumulative significance of these antioxidant system components in plant metal/metalloid stress tolerance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.