ArticleJournal of neural transmission (Vienna, Austria : 1996)2014
The impact of the nocturnal disabilities of Parkinson's disease on caregivers' burden: implications for interventions.
Article in Journal of neural transmission (Vienna, Austria : 1996), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Nocturnal Hypokinesia and Early Morning OFF in Parkinson's Disease: State-of-the-Art and Systematic Review of Treatment Availability.Current neurology and neuroscience reports · 2025Pooled it
- Risk factors and intervention of caregiver burden in Parkinson's disease: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- The impact of caregiving on quality of life in Parkinson's disease: A systematic review.International journal of geriatric psychiatry · 2023Pooled it
- Evaluation of Nocturnal Symptoms in Chinese Parkinson's Disease Patients Based on the PDSS-2 Scale: A Multicenter Cross-Sectional Study.Journal of Parkinson's disease · 2023Article
- Impaired night-time mobility in patients with Parkinson's disease: a systematic review.Frontiers in aging neuroscience · 2023Review
- Determinants of impaired bed mobility in Parkinson's disease: Impact of hip muscle strength and motor symptoms.NeuroRehabilitation · 2022Article
- Perceptions and meanings of living with Parkinson's disease: an account of caregivers lived experiences.International journal of qualitative studies on health and well-being · 2021Article
- Effects of Deep Brain Stimulation on Sleep-Wake Disturbances in Patients with Parkinson's Disease: A Narrative Review.Current neuropharmacology · 2021Review
- Cross-cultural differences in Parkinson's disease caregiving and burden between the United States and Mexico.Brain and behavior · 2020Article
- Mastering nocturnal jigsaws in Parkinson's disease: a dusk-to-dawn review of night-time symptoms.Journal of neural transmission (Vienna, Austria : 1996) · 2020Review
- Exploring Bedroom Usability and Accessibility in Parkinson's Disease (PD): The Utility of a PD Home Safety Questionnaire and Implications for Adaptations.Frontiers in neurology · 2018Article
- Transdermal Rotigotine Improves Sleep Fragmentation in Parkinson's Disease: Results of the Multicenter, Prospective SLEEP-FRAM Study.Parkinson's disease · 2015Article
- Neuropsychiatric Symptoms and Caregiver Burden in Parkinson's Disease.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) imposes a burden on those who care for the person afflicted. The objective of this study was to assess and analyze the main determinants of caregivers' burden, especially the nocturnal manifestations of PD. This multi-center, national, cross-sectional study included 89 patient-caregiver pairs. Caregiver self-assessments were performed with Hospital Anxiety and Depression Scale (HADS) and Zarit Caregiver Burden Interview (ZCBI). Patient self-assessments were performed with Modified Parkinson's Disease Sleep Scale (MPDSS), Nocturnal Akinesia Dystonia and Cramp Score (NADCS), HADS and Parkinson's Disease Quality of Life Questionnaire (PDQ-8). Most of the caregivers were employed women, and the majority had been permanently taking care of the patient for 6.8 ± 5.4 years. The study found that the ZCBI mean score of the caregivers significantly worsened as patients became more dependent (HY: 4-5, p = 0.036), and the mean ZCBI score of spousal caregivers (19.4; SD 15.5) was significantly higher than that of the offspring group (11.7; SD 7.9) (p = 0.008). Disease duration (r = 0.22), NADCS (r = 0.38), MPDSS (r = -0.36), PDQ-8 SI (r = 0.39) and HADS (total, anxiety and depression) scores (r = 0.46-0.49), and HADS (total, anxiety and depression scores (r = 0.37-0.52), had significant negative effect on caregivers' burden. Moderate association was found on MPDSS item 14 (r = 0.38) and NADCS akinesia score (r = 0.37). Patients' anxiety, nocturnal akinesia and the feeling of tiredness and sleepiness upon awakening in the morning were independent predictors of caregivers' burden (adjusted R2 = 0.46). Based on these findings, treatment of early mood symptoms of the patients and caregivers at risk may be helpful for the effective management of PD and it is also important to have well-designed psycho-educational and multicomponent interventions in the community for caregivers of persons with PD.
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