Evidence map›Paper›PMID 24681690›Full record

ArticleEvaluation review2013

Sensitivity plots for confounder bias in the single mediator model.

Matthew G Cox, Yasemin Kisbu-Sakarya, Milica Miočević, David P MacKinnon

Abstract readComparative Study
In one paragraph

Article in Evaluation review, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Trial
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  5. The association between rs6859 inmedRxiv : the preprint server for health sciences · 2024
    Article
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  8. The association between rs6859 inFrontiers in aging neuroscience · 2024
    Article
  9. Article
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  11. Estimating latent baseline-by-treatment interactions in statistical mediation analysis.Structural equation modeling : a multidisciplinary journal · 2023
    Article
  12. Article
  13. Teacher's Corner: An R Shiny App for Sensitivity Analysis for Latent Growth Curve Mediation.Structural equation modeling : a multidisciplinary journal · 2022
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew G CoxDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yasemin Kisbu-Sakarya
Milica Miočević
David P MacKinnon

Funding

Training in Child Mental Health/Primary PreventionT32MH018387 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 1987 to 2014
$3.8M
Estimating Mediation Effects in Prevention StudiesR37DA009757 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MACKINNON, DAVID P · 2015 to 2024
$3.5M
ESTIMATING MEDIATION EFFECTS IN PREVENTION STUDIESR01DA009757 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MACKINNON, DAVID P · 1996 to 2013
$2.6M
SCHOOL-BASED PREVENTION OF ANABOLIC STEROID USER01DA007356 · NIDA · OREGON HEALTH AND SCIENCE UNIVERSITY · PI MACKINNON, DAVID P · 1993 to 2001
$665k
NIDA NIH HHS R01 DA007356NIDA NIH HHS R01 DA009757NIDA NIH HHS R01DA009757NIDA NIH HHS R01DA07356NIDA NIH HHS R37 DA009757NIMH NIH HHS T32 MH018387NIMH NIH HHS T32 MH18387
6 · The paper itself

Abstract

backgroundCausal inference continues to be a critical aspect of evaluation research. Recent research in causal inference for statistical mediation has focused on addressing the sequential ignorability assumption; specifically, that there is no confounding between the mediator and the outcome variable.

objectivesThis article compares and contrasts three different methods for assessing sensitivity to confounding and describes the graphical depiction of these methods.

designTwo types of data were used to fully examine the plots for sensitivity analysis. The first type was generated data from a single mediator model with a confounder influencing both the mediator and the outcome variable. The second was data from an actual intervention study. With both types of data, situations are examined where confounding has a large effect and a small effect. SUBJECTS: The nonsimulated data were from a large intervention study to decrease intentions to use steroids among high school football players. We demonstrate one situation where confounding is likely and another situation where confounding is unlikely.

conclusionsWe discuss how these methods could be implemented in future mediation studies as well as the limitations and future directions for these methods.

Indexed as

Confounding Factors, EpidemiologicEvaluation Studies as TopicBiasHumansLinear ModelsModels, Statisticalcausal inferenceconfounder biasindirect effectsmediationsensitivity analysis

Identifiers

PMID24681690
PMCPMC4207278

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.